
Audrey Lapinaite
@sarkele1
Asst. Prof. at UCI
Interests: DNA&RNA modifications, CRISPR biology, precision genome editors, protein engineering
Trying out Mastodon: @[email protected]
ID: 2842593627
http://lapinaitelab.org 24-10-2014 15:07:22
1,1K Tweet
1,1K Followers
1,1K Following


We are searching for a highly motivated PhD student (m/f/d) interested in developing novel CRISPR 2.0 gene editing technologies for CAR-T cell engineering and cancer immunotherapy Universitätsklinikum Würzburg & Universität Würzburg #UniWürzburg. Please RT 🙏.


Our study on the effects of metal ion concentration on Cas12a specificity is now out as a Breakthrough Article in Nucleic Acids Res! Congrats to Ginny Giang Nguyen, Michael Michael Schelling and all the authors!




Our work describing extensive gene divergence on laboratory timescales with upgraded OrthoRep systems is now out in Science Magazine here - science.org/doi/10.1126/sc…. X thread describing the preprint is quoted below. Congratulations to Gordon Rix and team!

ABE8e: the Beyoncé of base editing—flawless dimerization, exclusive interactions, and unparalleled efficiency! 🎤 Check out our latest work: doi.org/10.1093/nar/gk… Giulia Palermo Audrey Lapinaite Souvik Sinha Aakash Saha #CRISPR #BaseEditing #ChemComp #MDsimulations


Do you want to know why hashtag#ABE8e is the most efficient adenine base editor? Read our paper with the amazing Audrey Lapinaite Nucleic Acids Res! The dimerization of TadA8e and its exclusive interactions with #CRISPR Cas9 boost #BaseEditing efficiency! academic.oup.com/nar/advance-ar…



New paper from our lab eLife - the journal. We show how #DirectedEvolution reshaped #CRISPR for expanding DNA recongition. Enhanced flexibility improves the recognition of canonical and alternative PAM sequences. elifesciences.org/reviewed-prepr…


