Audrey Lapinaite (@sarkele1) 's Twitter Profile
Audrey Lapinaite

@sarkele1

Asst. Prof. at UCI
Interests: DNA&RNA modifications, CRISPR biology, precision genome editors, protein engineering
Trying out Mastodon: @[email protected]

ID: 2842593627

linkhttp://lapinaitelab.org calendar_today24-10-2014 15:07:22

1,1K Tweet

1,1K Followers

1,1K Following

Karl Petri (@karl_petri) 's Twitter Profile Photo

We are searching for a highly motivated PhD student (m/f/d) interested in developing novel CRISPR 2.0 gene editing technologies for CAR-T cell engineering and cancer immunotherapy UniversitƤtsklinikum Würzburg & UniversitƤt Würzburg #UniWürzburg. Please RT šŸ™.

We are searching for a highly motivated PhD student (m/f/d) interested in developing novel CRISPR 2.0 gene editing technologies for CAR-T cell engineering and cancer immunotherapy <a href="/Uniklinikum_Wue/">UniversitƤtsklinikum Würzburg</a> &amp; <a href="/Uni_WUE/">UniversitƤt Würzburg #UniWürzburg</a>. Please RT šŸ™.
Dipa Sashital (@dsashital) 's Twitter Profile Photo

Our study on the effects of metal ion concentration on Cas12a specificity is now out as a Breakthrough Article in Nucleic Acids Res! Congrats to Ginny Giang Nguyen, Michael Michael Schelling and all the authors!

Chang Liu (@chang_c_liu) 's Twitter Profile Photo

Alexandra Paulk et al. have upgraded OrthoRep-driven antibody evolution by installing a rapid induction system for yeast display and new error-prone DNAPs for faster in vivo antibody diversification. Much more in this space soon! pubs.acs.org/doi/10.1021/ac…

RƩmi Buisson (@remibuisson) 's Twitter Profile Photo

We are hiring UC Irvine, a tenure-track faculty member at the Assistant or Associate Professor level with expertise in any area related to RNA biology, including microbiology, oncology, virology, structural biology, chemical biology, and genomics. recruit.ap.uci.edu/JPF09320

RƩmi Buisson (@remibuisson) 's Twitter Profile Photo

🄳Today pnas, we reported CRISPR-Translate, a genome-wide CRISPR-Cas9 knockout screen-based method designed to identify factors regulating translation. We discovered IRF2 as a novel regulator of OAS3/RNase L-mediated RNA decay during viral infections. pnas.org/doi/10.1073/pn…

Chang Liu (@chang_c_liu) 's Twitter Profile Photo

Our work describing extensive gene divergence on laboratory timescales with upgraded OrthoRep systems is now out in Science Magazine here - science.org/doi/10.1126/sc…. X thread describing the preprint is quoted below. Congratulations to Gordon Rix and team!

Pablo Arantes - @pabloarantes.bsky.social (@pablitoarantes) 's Twitter Profile Photo

ABE8e: the BeyoncĆ© of base editing—flawless dimerization, exclusive interactions, and unparalleled efficiency! šŸŽ¤ Check out our latest work: doi.org/10.1093/nar/gk… Giulia Palermo Audrey Lapinaite Souvik Sinha Aakash Saha #CRISPR #BaseEditing #ChemComp #MDsimulations

ABE8e: the BeyoncĆ© of base editing—flawless dimerization, exclusive interactions, and unparalleled efficiency! šŸŽ¤
Check out our latest work: doi.org/10.1093/nar/gk…
<a href="/palermo_lab/">Giulia Palermo</a> <a href="/Sarkele1/">Audrey Lapinaite</a> <a href="/sou_svk/">Souvik Sinha</a> <a href="/aakashsahha/">Aakash Saha</a> 
#CRISPR #BaseEditing #ChemComp #MDsimulations
Giulia Palermo (@palermo_lab) 's Twitter Profile Photo

Do you want to know why hashtag#ABE8e is the most efficient adenine base editor? Read our paper with the amazing Audrey Lapinaite Nucleic Acids Res! The dimerization of TadA8e and its exclusive interactions with #CRISPR Cas9 boost #BaseEditing efficiency! academic.oup.com/nar/advance-ar…

Do you want to know why hashtag#ABE8e is the most efficient adenine base editor? Read our paper with the amazing <a href="/Sarkele1/">Audrey Lapinaite</a> <a href="/NAR_Open/">Nucleic Acids Res</a>! 
The dimerization of TadA8e and its exclusive interactions with #CRISPR Cas9 boost  #BaseEditing efficiency! 
academic.oup.com/nar/advance-ar…
Ronald Breaker (@ronbreaker) 's Twitter Profile Photo

#ncRNA molecules are stranger than you think. We propose that OLE RNA is bacteria's functional mimic of #mTOR. The Das lab at Stanford proposes OLE RNA penetrates cell membranes! They also find that RNAs we called ROOL and GOLLD form 8-membered nanocages. biorxiv.org/content/10.110…

#ncRNA molecules are stranger than you think. We propose that OLE RNA is bacteria's functional mimic of
#mTOR. The Das lab at Stanford proposes OLE RNA penetrates cell membranes! They also find that RNAs we called ROOL and GOLLD form 8-membered nanocages. biorxiv.org/content/10.110…
Audrey Lapinaite (@sarkele1) 's Twitter Profile Photo

Looking for a motivated Postdoctoral Fellow to join our team at UC Irvine! Contribute to cutting-edge research on developing innovative genome editors for treating ocular genetic diseases. #Postdoc #GenomeEditing #OcularResearch #UCI

Looking for a motivated Postdoctoral Fellow to join our team at UC Irvine! Contribute to cutting-edge research on developing innovative genome editors for treating ocular genetic diseases. #Postdoc #GenomeEditing #OcularResearch #UCI
Giulia Palermo (@palermo_lab) 's Twitter Profile Photo

New paper from our lab eLife - the journal. We show how #DirectedEvolution reshaped #CRISPR for expanding DNA recongition. Enhanced flexibility improves the recognition of canonical and alternative PAM sequences. elifesciences.org/reviewed-prepr…

New paper from our lab <a href="/eLife/">eLife - the journal</a>. We show how #DirectedEvolution reshaped #CRISPR for expanding DNA recongition.  
Enhanced flexibility improves the recognition of canonical and alternative PAM sequences.
elifesciences.org/reviewed-prepr…
Brady Cress (@bradyfcress) 's Twitter Profile Photo

Dive into our lab’s first peer-reviewed publication—co-led with our friends Ben Adler and Muntathar Al-Shimary from the Doudna lab! If you’ve already read the preprint, don’t miss the new updates: doi.org/10.1038/s41564… Nature Microbiology

Giulia Palermo (@palermo_lab) 's Twitter Profile Photo

New study bioRxiv We revea, how TnsC filaments form and grow in #CRISPR-associated transposons using #FreeEnergy sims & introduce #DeepLearning-based Graph Attention Networks for decoding biomolecular systems! biorxiv.org/content/10.110… #GNN #StructuralBiology

New study <a href="/biorxivpreprint/">bioRxiv</a> 
We revea, how TnsC filaments form and grow in #CRISPR-associated transposons using #FreeEnergy sims &amp; introduce #DeepLearning-based Graph Attention Networks for decoding biomolecular systems!
biorxiv.org/content/10.110…
#GNN #StructuralBiology