Very excited to share our work on HIV, out this week in nature. We sort and RNA-seq infected cells solely based on the detection of provirus DNA. Infected CD4 T cells have unique signatures that help to explain HIV persistence in vivo. nature.com/articles/s4158…

Authored by Andrew G. Soerens et al, we show that #Tcells are capable of proliferating in response to iterative stimulation for over 10yrs! And produce enough progeny to occupy a volume 30,000x the Earth's volume! nature nature.com/articles/s4158…

check out our paper from my time as a postdoc in Masopust Vezys Lab lab! cellular and humoral immunity working together🤝! Resident memory T cells induce rapid (within hrs) vascular permeability in the female reproductive tract, enabling infiltration of neutralizing antibodies 1/5

Very excited to share our work in Science Immunology on the migration properties of CD8+ tumor-infiltrating lymphocytes (TILs)! Using 🐭 models and parabiosis, we uncovered unique features of tumor-resident T cells. Spoiler 🚨tumor ≠ healthy tissue. science.org/doi/10.1126/sc… 1/7

Our study on human T cell memory formation during infancy and childhood revealing progressive maturation of tissue resident subsets in mucosal sites is online—thanks to Thomas Connors, Shivali Verma and great collaborators @AYatesGroup, Peter Sims @bruskolab. cell.com/immunity/fullt…

Michael is the godfather of viral pathogenesis and the reason so many labs have been able to use LCMV (and other viruses) for fundamental discoveries. He was an inspiration and giant in the field. I will be forever grateful to the advice he gave me early in my career. RIP MBAO

Thrilled to announce the opening of the Srivatsan Lab (srivatsan-lab.com) at the Fred Hutch Cancer Center. The lab will be building new sequencing technologies to understand how our cells and bodies form over the course of development.

CD39 is expressed on functional effector and tissue resident memory CD8+ T cells biorxiv.org/cgi/content/sh… #biorxiv_immuno

Very excited to share our paper led by Madison (Maddi) Strine, PhD Intestinal tuft cell immune privilege enables norovirus persistence | Science Immunology science.org/doi/10.1126/sc… 1/n

The Thompson lab is officially live! Excited to announce that I recently accepted a faculty position Molecular Microbiology and Immunology at JHSPH studying immunometabolic regulation of vaccine responses. Kicking off the new lab with my first purchase, obviously a Cytek Biosciences flow cytometer!

Cutting Edge: First Lung Infection Permanently Enlarges Lymph Nodes and Enhances New T Cell Responses journals.aai.org/jimmunol/artic…

Great postdoc opportunity with Beura_lab@Brown. #AAI2024

Delighted to share our new work Jameson Hogquist labs CFI-UMN on cytokine regulation of homeostatic memory CD8 T cells biorxiv.org/content/10.110… tl;dr homeostatic circulating and resident memory CD8 T cells are resilient to loss of IL-7Rα (surprise!) Please RT Thread follows

We are seeking 1-2 talented immunology students to join our team in the tropical and picturesque region of North Queensland, where summers are endless and sunshine is abundant.

Excited to share our perspective on resident memory T cells in solid tumors!!Huge thanks to Immunity and Jodi Gullicksrud. Amazing figures and artwork from Katarina Cheng and support from the whole Masopust Vezys Lab team. kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…

Our paper describing in vitro resident memory T cell differentiation in an epithelial organoid model is out at Cell Reports doi.org/10.1016/j.celr…. If you are excited about T cells and reproductive mucosa, we are looking for postdocs-apply.interfolio.com/145385

Hear from a talented lineup of immunologists next Wednesday, Sept 18 featuring Zuri Sullivan, Alex Wells, Djenet Bousbaine, Dr. Valeria M. Reyes Ruiz, Maria Cecilia Canesso, Dr Becs, Liwen Deng, & Nagela Ghabdan Zanluqui. Register: bit.ly/ScrippsLeaders

Our NIH grant to discover coronavirus antiviral meds was terminated today. With this grant, we had developed a better SARSCoV2 inhibitor than Paxlovid, and we recently discovered an improved drug that looks better than Pfizer's own second-generation inhibitor.

Through sex-inclusive research, we find that meningeal regulatory T cells suppress pain sensitivity under the control of ovarian hormones. science.org/doi/10.1126/sc… by Élora Midavaine, at UC San Francisco, in Science Magazine.