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Last week we started into the season with our annual winter lab party. This year: Curling! It was big fun 🎅🧑‍🎄🎄#afterwork #science #labparty

...and out of our #labparty we made a christmas calendar out of it! Every day, a lab member avatar from the party is waiting behind a calendar door and offers some sweets for a lucky person 👩‍🔬🔬🎄🧁🍫🍩🍬🍭🍪

And now the manuscript got published at Nature Communications. What a nice start into 2024! Thanks to Anna Worthmann and her group as well as all other collaborateurs for this journey. #HappyNewYear UKE Hamburg nature.com/articles/s4146…

New publications from our TRR333 PIs Christian Schlein Anna Worthmann ! What a great start for the new year 2024! Huge congrats!

Ever wondered what determines the composition of complex lipids? Here, Worthmann (Anna Worthmann) et al. show that endogenous lipid synthesis controls the use of #PUFA and thus determine the therapeutic benefit of #omega3 fatty acid supplementation. Christian Schlein nature.com/articles/s4146…

Vollste Zustimmung. Die geplante Reform macht es leider nur noch schlimmer - man kann keiner Person guten Gewissens raten eine wissenschaftliche Karriere in D anzustreben.

Excellent summary describing both Lp(a) and what to do if high.

This is a medical first- despite drug approvals for TG >500, none were shown to reduce pancreatitis. The Balance study required great science, a great drug, great study design, and great execution to succeed. Congrats to Ionis for 15 yrs of dedication and perseverance to

Man stelle sich vor, dass man als Politiker nach einer Legislaturperiode entweder Minister ist oder gekündigt wird #WissZeitVG

Very much looking forward to meet you at the #ESHG2024 ! Please get in touch with us at Posters p05.013, p08.018 and p08.043 for some metabolic Research 🧑🏽‍🔬🔬🧪🧬

...and last but not least at #eshg2024: 👩‍🔬Our analyst Ida Paramonov presents the disease-causing mitochondrial variants she has worked on in Solve-RD 🙌Great effort, many congratulations! #CNAG #RareDiseases #FindACure #Genomics #GeneticDiseases #DiagnosticOdyssey

Preprints need to gain more visibility. With the current review process they are years ahead of the conventional publishing record. If you are a funding body, pay reviewers to evaluate preprints to make them fully eligible as track record.

Good morning ☕🌞

My first author paper from my thesis work has been uploaded to BioRxiv! We identified Mecr as important for T cell fitness in in vivo CRISPR screens. I have further worked with Mecr and am the first to show it regulates T cell function and metabolism. biorxiv.org/content/10.110…

Today, we report that cholesterol-induced inflammation in adipocytes is under control of the Nfe2l1-ATF3 pathway. Proteasome-mediated proteostasis is vital to suppress insulin resistance and atherosclerosis in mice and is linked to obesity in humans. 👇 biorxiv.org/content/10.110…

This opens a new avenue for the treatment of genetic diseases - impressive work

"Lipoprotein(a) and cardiovascular disease" review published today in The Lancet: 50 days' free access: authors.elsevier.com/a/1jlsNV-4XOtaS Please share and resend for others to download. Bottom line: measure Lp(a) in all once in a lifetime and stay tuned for coming Lp(a)-lowering therapy!

The Danish Diabetes and Endocrine Academy Postdoctoral summit 2024 was a blast! Honored to receive the “Best Poster Award” and the “Second Best Poster Pitch Award” for our lab's recent collaborative work. Anna Worthmann Christian Schlein. Heartfelt thanks to the organizers and the committee for an incredible week!

Honored to have received the Mito Foundation travel award to represent Christian Schlein and present our work on mitochondrial fatty acid synthesis at AussieMit Conference 2024! Looking forward to this opportunity and meeting you all there! CRC/TRR-BATenergy #mitochondria #lipids #brownfat

Familial hypercholesterolemia was recorded in Danish registries since 1978, as the only country in the world. In both women and men in 1978 through 2021 age at death normalized but not age at coronary heart disease. Eur Heart J just published: academic.oup.com/eurheartj/adva…