Our recent work on Bioconjugatable constrained #cyanine is finally out in Angewandte Chemie. Feel free to reach out if you would like to try these dyes! Incredible collaboration between us at SchnermannLab and SauerLab Tinnefeld Lab, Cordes lab, Viktorija Glembockyte onlinelibrary.wiley.com/doi/10.1002/an…

Targetable Conformationally Restricted Cyanines Enable Photon-Count-Limited Applications (Schnermann) SchnermannLab Siddharth Sai Viktorija Glembockyte Tinnefeld Lab SauerLab Gerti Beliu Dr. Venu Gopal Bandi #openaccess thanks to #projektDEAL onlinelibrary.wiley.com/doi/10.1002/an…

Happy to see this out! Congrats to Usama and the team! More to come using optical imaging to study ADC chemistry.

Excited to see this out!! Congrats to all the coauthors!!

Excited to see #Cyanine PACT out on ChemRxiv today. This straightforward method enables spatiotemporal control over cell tracking. SchnermannLab Lenka Stackova @FredNatLab @NCIResearchCtr National Cancer Institute #Hisataka_Kobayashi #chemtwitter doi.org/10.26434/chemr…

Interesting strategy to track cells in live animals by leveraging light-induced cyanine phototruncation. This represents a nice example of applying mechanistic understanding (bit.ly/3trB49y) to develop a tailored dye platform with exciting applications.

Thrilled to see this story finally out today in J. Am. Chem. Soc.. Here, we pioneer a first-in class fluorescence "turn-on" reaction of cyclopropenones and phosphines for multicomponent, real-time imaging in live mammalian cells. (1/4) tinyurl.com/Heiss-JACS-2022

Last chance to submit an abstract for an oral slot and/or a poster presentation. Amazing already confirmed speakers contribute to an amazing conference regarding fluorescence and its applications. MAF2022 in Gothenburg Sweden! nanoFRET - Niko Hildebrandt app.bwz.se/gothiatowers/b…

Thapaliya et al. National Cancer Institute @FredNatLab studied the effect of functional groups on the targeting and accumulation of monoclonal #antibody #conjugates using masked heptamethine cyanines, finding that zwitterionic probes exhibit excellent properties. pubs.acs.org/doi/10.1021/ac…

Thanks Art!!

Stoked to see our recent J. Am. Chem. Soc. communication out!!! This report describes spatially controlled #cyanine #phototruncation for temporal in vivo cell tracking. Incredible collaboration between SchnermannLab, Klan lab, and Kobayashi lab!! Lenka Stackova pubs.acs.org/doi/10.1021/ja…

.Mara Saccomano discusses novel short wave infrared fluorescent dyes and technological imaging advances for multicolor fluorescence guided surgeries. Nature Methods Helmholtz Munich | @HelmholtzMunich National Cancer Institute @NCICancerBio SchnermannLab OliverTBruns #JRNLclub jrnlclub.org/research-films…

Excited to share our recent review on Antibody-drug conjugates from the #Trastuzumab lens! #ADC NIH SchnermannLab Bioconjugate Chem National Cancer Institute pubs.acs.org/doi/10.1021/ac…

New in Bioconjugate Chem - Matikonda et al. review structure-activity relationships of antibody-drug conjugates and compare existing and emerging conjugate technologies! go.acs.org/1Cy

Fantastic Review SchnermannLab Structure–Activity Relationships of Antibody-Drug Conjugates: A Systematic Review of Chemistry on the Trastuzumab Scaffold pubs.acs.org/doi/10.1021/ac…

HUGE collaborative effort as we aim to bring new intraoperative imaging technologies to enhance surgical outcomes in patients with neuroendocrine tumors! Congrats to the whole team Jennifer Bailey-Lundberg Naruhiko Ikoma MD MS Hop S. Tran Cao SchnermannLab Po Hien Ear, PhD NET Research Foundation NANETS

Abstracts Due: 4/2! Talk #Imaging #Biosensors #Chemogenetics #Probes #Chemiluminescence #Bioluminescence #Microscopy & more at the Optical Probes Conf. 6/4-8. #OPCSRC Info: bit.ly/3WqQrdK Students: $150 off Organizers: Liz New Amandeep Kaur The Cosa Group SchnermannLab

We are recruiting for a faculty position in the Chemical Biology Lab at the NCI! Come join a phenomenal group of scientists. SchnermannLab, @Joel_Peptides, Euna Yoo, Joseph Barchi Jr. , @j_sleeve, @doc_jlmeier bit.ly/405Pfi3

Submit your abstract by next week! Share your optical probes research with your peers at this important brand-new conference in Palm Springs for a short talk or an in-person poster. #OPCSRC Amandeep Kaur SchnermannLab Liz New The Cosa Group Info: bit.ly/42JGr3D

Method To Diversify Cyanine Chromophore Functionality Enables Improved Biomolecule Tracking and Intracellular Imaging | Journal of the American Chemical Society National Cancer Institute @NCIResearchCtr #Cyanine #Chromophore #Biomolecule #Tracking #Intracellular #Imaging pubs.acs.org/doi/10.1021/ja…