🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

🎉 Felicitaties voor Ton Schumacher @schumacher_lab die met Team MATCHMAKERS door Cancer Grand Challenges is geselecteerd om in vijf jaar tijd tot $25 miljoen te ontvangen om een ​​van de zwaarste uitdagingen op het gebied van kanker aan te gaan

What a ride to be leading this effort to solve T cell recognition - incredible opportunity and team, and 5 years to throw everything we have at it. Thanks Cancer Grand Challenges National Cancer Institute The Mark Foundation for Cancer Research for the award - and Koch Institute at MIT MIT Dept of BE Ragon Institute for the continual support

Right in time to celebrate the lab’s 4 yr anniversary, we are excited to share our new work in Cancer Discovery, in which we explore a CD8-targeted IL2 to revive dysfunctional T cells in anti-PD1 resistant human cancers 1/n aacrjournals.org/cancerdiscover…

Researchers from the group of John Haanen and Ton Schumacher Lab have successfully developed a novel method that enables the identification of T cell receptors at an unprecedented scale ➡️ bit.ly/3Ql6ObG

Out now: Discovery of tumor-reactive T cell receptors by massively parallel library synthesis and screening by Ziva Morec in Nature Biotechnology #publicationoftheweek ➡️ go.nature.com/3UopuYZ

Ton Schumacher is closing #CancerHostTI24 discussing neoantigens and neoadjuvant therapy. With his research group he created technologies to dissect T cell responses in cancer and contributed to the development of adoptive T cell therapies and neoadjuvant cancer immunotherapy.

Fantastic Keynote at #CIMT2024 by Ton Schumacher Lab The Netherlands Cancer Institute on rethinking our knowledge of #ICB efficacy and going beyond toward cracking the T cell receptor-cancer recognition code #TCR. Amazing endeavor in pushing forward personalized #immunotherapy Cancer Immunotherapy Cancer Research UK National Cancer Institute 🔬🧬🧫

p53-independent apoptosis occurred through a ribotoxic stress response. The Hugo Snippert and Ton Schumacher Lab showed that ribosome stalling occurred in patient-derived organoids and healthy human T cells. This highlights ribosome stalling as a new signaling event upon DNA damage.

Large-Scale Mapping of TCR-pMHC Interactions: Ton Schumacher will address this topic in a keynote lecture at the AACR Special Conference on Tumor Immunology and Immunotherapy (October 18-21, Boston). Learn more: bit.ly/3zRDJ2b #AACRtii24 Ton Schumacher Lab

Dissecting T Cell Recognition of Human Cancer: Ton N. Schumacher will address this topic in a keynote address at the AACR IO Conference on Discovery and Innovation in Cancer Immunology (Feb 23-26, 2025; Los Angeles). Learn more: bit.ly/3XBR2fl #AACRIO25 Ton Schumacher Lab

Congratulations David Baker (University of Washington, member of #CancerGrandChallenges team MATCHMAKERS), who's won the 2024 Nobel Prize in Chemistry for his pioneering work building new kinds of proteins! 👏 More about MATCHMAKERS, funded by Cancer Research UK National Cancer Institute The Mark Foundation for Cancer Research 👉 cancergrandchallenges.org/matchmakers

Large-scale Mapping of TCR-pMHC Interactions: Ton Schumacher addressed this topic in a keynote address Sunday evening at the AACR Special Conference on Tumor Immunology and Immunotherapy. #AACRtii24 Ton Schumacher Lab

.Ton Schumacher Lab was bestowed the 2024 ESMO Award for Immuno-Oncology. He will deliver his award lecture on Wednesday, 11 December 2024 at the opening session of #ESMOImmuno24. 📌ow.ly/FiiN50U0iab

We’re in Boston for the 1st annual meeting of the Cancer Grand Challenges Challenges MATCHMAKERS team! The team, which we sponsor with Cancer Research UK & National Cancer Institute, is creating tools to predict T cell antigen specificity, which could unlock more effective immunotherapies. cancergrandchallenges.org/challenges/act…

#ESMOImmuno24: According to the 2024 ESMO Immuno-Oncology Awardee, Ton Schumacher Lab, tackling the T-cell receptor challenge w/ vast datasets and cutting-edge high-throughput methods may pave the way for advances in #immunotherapy. #ESMODailyReporter 📌ow.ly/rZUO50Up0BE

🏆 Congrats to Ton Schumacher Ton Schumacher Lab of the NKI and Oncode Institute for receiving the ESMO Award for Immuno-Oncology 2024! His work on T-cells and immunotherapy is revolutionizing cancer treatment ➡️ bit.ly/3ZQcpM8 #CancerResearch #ImmunoOncology #ESMOImmuno24

New from our Future Leaders Spotlight series, where we feature early-career researchers on our funded teams 💡 Here, Benoit Nicolet of MATCHMAKERS shares what it's like being on this scientific dream team (and receiving emails from a #NobelPrize winner!): bit.ly/4iN1dY9

It's not the models, it's the data! We show that a substantial proportion of a widely used TCR-pMHC database does not functionally validate, causing underestimation of performance of TCR-pMHC prediction models.🧵 biorxiv.org/content/10.110…