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New research from John Chang identifies context- and anatomy-specific roles for the transcription factor #Foxo1 in regulating intestinal tissue-resident memory CD8 #TCells in mice. Learn more in Science #Immunology: scim.ag/4cuCVzh

A new Science #Immunology study in mice describes a stress-induced brain-skin axis that reduces production of the antimicrobial peptide #cathelicidin in dermal #fibroblasts and promotes Staph aureus infections. scim.ag/3E1Al7m

A new Science #Immunology study demonstrates how intrinsic overexpression of Bcl11a preserves #Hematopoietic #StemCell function (HSC) but shows that extrinsic overexpression accelerates HSC exhaustion and decline by enhancing FcR signaling. scim.ag/3RHOSbh

A new Science #Immunology study in mice describes how the transcription factor #Foxo1 represses maintenance of early #TRM cells in some parts of the small intestine, but sustains them in other parts and in the colon. scim.ag/4cuCVzh

Researchers have identified a subset of #regulatory #Tcells enriched in the decidua that promote maternal-fetal immune tolerance during early #pregnancy. 山东大学 SHANDONG UNIVERSITY Learn more in Science #Immunology: scim.ag/4cAgw3E

Scientists have identified lung #endothelial cells as sources of TGFβ1 that guide the development and function of lung #InterstitialMacrophages in mice. GIGA-ULiège Université de Liège Read more in Science #Immunology: scim.ag/3Enz9LF

A new Science #Immunology study shows that CCR8+ decidual regulatory #Tcells are depleted in patients with recurrent #pregnancy loss (RPL) and pregnant mouse models, which could inform future therapeutic targets for RPL. scim.ag/4cAgw3E

A new Science #Immunology study in mice describes how disrupting #TGFβ receptor signaling in lung #InterstitialMacrophages causes premature age-associated defects such as increased fibrosis and loss of elasticity. Qiang BAI scim.ag/3Enz9LF

Scientists show that type I regulatory T (Tr1) cells dominate CD4+ #Tcell responses and underlie long-term immunity in young children and adults repeatedly exposed to #malaria. Stanford Medicine Jagannathan Lab Read more in Science #Immunology: scim.ag/42sDt5p

Scientists have identified extensive interactions between T and B cells in the #meninges that promote CNS inflammation in mouse models of #MultipleSclerosis. Universität München Read more in Science #Immunology: scim.ag/4jP19Xz

A recent Science #Immunology Review highlights the role of #DendriticCells in shaping TCell antitumor responses and explores how this interplay could be harnessed for cancer #vaccines. scim.ag/42pA7Am #DayOfImmunology

In a recent Science #Immunology Review, researchers discuss ways in which genetic abnormalities enable #cancer cells to evade #antitumor immunity and resist treatment. scim.ag/4c7cJuz #DayOfImmunology

A new Science #Immunology study highlights the role of type I regulatory T cells in long-term #antimalarial immunity in Ugandan children and adults chronically exposed to #Plasmodium falciparum. Jason Nideffer Prasanna Jagannathan scim.ag/42sDt5p

A new Science #Immunology study in mice suggests that ectopic lymphoid follicles in the meninges may contribute to disease progression in #MultipleSclerosis by promoting T–B cell interactions that enhance #autoimmune inflammation. scim.ag/4jP19Xz

Scientists have discovered that the uptake of apoptotic #neutrophils can switch #AlveolarMacrophages to favor inflammation resolution over antibacterial responses in mice. UKGM Gießen und Marburg Learn more in Science #Immunology: scim.ag/4dgWmfD

Using single-cell transcriptomics and high-resolution imaging, scientists have characterized how fibroblastic reticular cells help reorganize human #LymphNodes during #inflammation. Learn more in Science #Immunology: scim.ag/3RNMb8m

Scientists have shown that type I and type II #interferons shape the formation of #thymic epithelial cells in the thymic medulla and cortex during early human development. Stanford Pediatrics Learn more in Science #Immunology: scim.ag/3Yobod7

A new Science #Immunology study demonstrates that neutrophil-derived #myeloperoxidase can alter mitochondrial function in #AlveolarMacrophages, promoting inflammation resolution and blunting antibacterial activity. Herold Lab scim.ag/4dgWmfD

A new Science #Immunology study describes how inflammation leads to interactions between perivascular #ReticularCells and macrophages in immune niches within human #lymph nodes. scim.ag/3RNMb8m