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Understanding how #proteins interact inside living cells is fundamental to biology. A new study from the lab of Dr. Max Prigozhin at MCB_Harvard introduces a novel method that quantifies protein-protein interactions at nanoscale resolution in cells. bit.ly/4klBplK

🚨 New preprint 🚨 We introduce Generative Distribution Embeddings (GDEs) — a framework for learning representations of distributions, not just datapoints. GDEs enable multiscale modeling and come with elegant statistical theory and some miraculous geometric results! 🧵

Researchers at Massachusetts Institute of Technology (MIT) led by Dr. Scott Manalis have developed a technique that rapidly measures #CellDensity. The method could help predict whether immunotherapies will work in a patient or how a tumor will respond to drug treatment. 💊 Learn more: bit.ly/45lX0Gn

We were thrilled to welcome legendary NFL quarterback Tom Brady to the Ragon Institute earlier this month! We’re grateful to Tom Brady for his enthusiasm and support for scientific discovery, and we are honored to have hosted him.

Researchers from the Broad Institute have developed a computational approach that can efficiently predict the location of any protein in any human cell line, even when both protein and cell have never been tested before. 🔎 bit.ly/4jhg4sY

Congratulations to Dr. Jiaxian Shen, a postdoc studying the role of the gut #microbiome in inflammatory bowel disease, on being a 2025 Poster of Distinction winner! 🎉 Learn more about her research in this Q&A: bit.ly/3H7ypLr

Tammy T. Nguyen, MD, PhD, will be the new Fuller Foundation Term Chair in Diabetes on July 1. She will look at #diabetes complications and strategies to prevent foot amputations: direc.to/nnpQ UMassDiabetes UMass Memorial Health UMassVascular UMass Chan Giving tammytnguyen

Congrats to the lab of Dr. Ana Fiszbein at Boston University on their new Molecular Cell study! 👏 It shows that U1 snRNP regulates alternative promoter activity in human cells by inhibiting premature polyadenylation. Read the paper: bit.ly/4kzOrMM

From investigating genome-wide associations in health and disease to probing individual molecular mechanisms, Whitehead Institute researchers span the continuum of scales across size, time, and process to reshape our understanding of biology: wi.mit.edu/series/underst…

By combining information from many large datasets, Massachusetts Institute of Technology (MIT) researchers have identified several new potential targets for treating or preventing #Alzheimer’s disease. Check out the newly identified genes and pathways, including one involved in DNA repair: bit.ly/4mEbw2q

Researchers at the Ragon have made a significant discovery about how antibodies can directly enhance the body’s ability to fight Mycobacterium tuberculosis (Mtb), the bacteria responsible for TB. Read more: ragoninstitute.org/2025/05/alter-… #Tuberculosis #TB #Antibodies #Immunity

Researchers at the Broad Institute have developed a way to edit the genetic sequences at the root of #Huntington’s disease and Friedreich’s ataxia. 🧬 The findings appeared in Nature Genetics and come from the lab of gene-editing pioneer Dr. @DavidRLiu: bit.ly/4kS3Vff

Philip ‘Terry’ Ragon, founding benefactor of the Ragon, and Bruce Walker, MD, our founding director, were spotlighted in a Forbes Africa article on the Ragon Institute's significant involvement in HIV research in Africa. Read the article here: forbesafrica.com/daily-cover-st…

David R. Liu works on #science that gives humans more say over their destinies: news.harvard.edu/gazette/story/… #chemtwitter #CRISPR

Delighted to have our work on Polygenic Modifiers of #TelomereBiologyDisorders, led by Michael Poeschla, along with Sasha Gusev, Mitchell Machiela, Sharon A. Savage, M.D., Tummala H, and others, published as an advanced online paper in Journal of Clinical Investigation today:

Researchers at the Broad Institute have created a pipeline for discovering unique combinations of molecules that increase the effectiveness of #antibiotics against drug-resistant bacteria. ✏️ Abstract: bit.ly/4kry8lu 📰 Press Release: bit.ly/3T5TSap

Understanding Dopamine Neurons on Multiple Timescales Paul Masset Pablo Tano nature HyungGoo Kim Athar N Malik, MD, PhD Alexandre Pouget Rachelle Gaudet MurthyLab at Harvard Catherine Dulac nature mcb.harvard.edu/department/new…

Scientists at McGovern Institute and Broad Institute have re-engineered a compact RNA-guided enzyme they found in bacteria into an efficient, programmable editor of human DNA. Learn more about their novel protein NovaIscB: bit.ly/43MTpPi #GeneticEngineering

We've been asking Whitehead Institute scientists to give us their elevator pitch! In the first installment of #Sciencein60, grad student Xochitl Luna describes her research on microglia, the brain's resident immune cells that play a role in MS. Xochitl Luna Olivia Corradin

Researchers at the Ragon Institute have made a significant discovery about how antibodies can directly enhance the body’s ability to fight Mycobacterium #tuberculosis. 🦠 Learn more about the work from Drs. Galit Alter, Sarah Fortune, and Bryan Bryson: bit.ly/4mP3fZC