🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

I am very proud of the superstar postdoc Haojun Yang, who discovered how to translation control underlying fasting and ketogenic diet in health and cancer. nature.com/articles/s4158…

Off to CSHL Translational Control meeting!! #cshltranscon

Absolutely beautiful day for exciting findings in translational control here at CSHL. We cannot wait to share our interesting new work on translational control in cancer! Davide Ruggero Duygu Kuzuoglu Ozturk

Lots of interest and excitement about our forthcoming research looking at how PDAC regulates Myc protein levels. So glad I could share this story with the translational control community. #cshltranscon

Davide Ruggero characterized the structure of Myv 5’UTR and a key RNA binding protein that regulates its translation level by interacting with specific structural motifs. Cool work

We are so pleased to share our new work looking at the selective production of the oncogene Myc in PDAC. Moving one step closer to novel ways to target a deadly cancer driver. Thank you to Davide Ruggero RNA Canada|Canadian Consortium of RNA Researchers

☕️Joanna Kovalski, Davide Ruggero & co perform a genome-wide CRISPRi screen and identify RBM42 as a ribosome-associated protein that modulates MYC translation and an #oncogenic mRNA program required for #PancreaticCancer growth. 👉🏼rdcu.be/ecb4e bit.ly/41rGfGb

A tour de force in deciphering in action the intriguing dynamic composition of ribosomes in vivo. Beautiful work! Congrats to all Barna Lab!

Delighted to share our most recent preprint led by the incredible Jessenya Mil and Jose Soto! In this study, we generated a metabolomic atlas of human cortical development and discovered that the pentose phosphate pathway regulates radial glia cell fate. biorxiv.org/content/10.110…

An important resource for the field! Excited to use these new tools to study a critical, yet under-appreciated mechanism of translational specificity. Congrats Barna Lab Kathrin Leppek!

Exciting and boundary-pushing findings out today helmed by the talented Duygu Kuzuoglu Ozturk. Beautiful work bridging therapeutic efficacy to molecular mechanisms unveiling the hidden layer of translational control within RNA structure. Congrats to all co-authors in Davide Ruggero lab.

I am excited to highlight new research out now in Nature Cell Biology that digs into the question of how a "general" translation factor, PABPC1, can drive #CML progression & drug resistance, including new targeted therapies. 👉nature.com/articles/s4155… ☕️nature.com/articles/s4155…