K. Patrick Seastedt, MD, FACS (@seastedtmd) 's Twitter Profile
K. Patrick Seastedt, MD, FACS

@seastedtmd

Thoracic Surgeon @RoswellPark Cancer Center. Cardiothoracic surgery @harvardmed, resident @WCMSurgery, former Surgeon @usairforce, AI researcher and proud Dad

ID: 1262498184879898629

linkhttps://www.linkedin.com/in/kenneth-patrick-seastedt-md-mba-facs-94a17b168 calendar_today18-05-2020 21:40:11

132 Tweet

222 Followers

467 Following

Jarushka Naidoo (@drjnaidoo) 's Twitter Profile Photo

Can a cfDNA fragmentomic assay assist in lung cancer screening? - prospective case-control study in >900pts - 84% sensitivity, across stages - (+LDCT)=⬇️no. needed to screen to just 76 Next step validate in prospective cohorts Cancer Discovery OncoAlert #LCSM aacrjournals.org/cancerdiscover…

Can a cfDNA fragmentomic assay assist in lung cancer screening?

- prospective case-control study in >900pts 
- 84% sensitivity, across stages 
- (+LDCT)=⬇️no. needed to screen to just 76

Next step validate in prospective cohorts <a href="/CD_AACR/">Cancer Discovery</a> <a href="/OncoAlert/">OncoAlert</a> #LCSM aacrjournals.org/cancerdiscover…
Brendon Stiles (@brendonstilesmd) 's Twitter Profile Photo

Love this approach - "Trailblazer" in Cancer Cell. Neoadjuvant chemo-ICI in marginally resectable patients. Led to 25% resection rate and good EFS/OS in both arms. Surgery and RT both safe. Shouldn't we consider giving our best therapy up front?

Love this approach - "Trailblazer" in <a href="/Cancer_Cell/">Cancer Cell</a>.  Neoadjuvant chemo-ICI in marginally resectable patients. Led to 25% resection rate and good EFS/OS in both arms. Surgery and RT both safe.  Shouldn't we consider giving our best therapy up front?
Jonathan Spicer MD PhD (@doctorjspicer) 's Twitter Profile Photo

I think we are fooling ourselves if we think that anatomic staging with CT/PET/brain MR in unresectable stage III does much to reduce the proportion of patients with underlying micrometastatic disease, especially in EGFR-mutated disease! So many of these patients even with

Jonathan Spicer MD PhD (@doctorjspicer) 's Twitter Profile Photo

We have these data from CM816. Return to baseline QoL occurs regardless of surgical access or extent of surgery. These are not really as relevant considerations as the importance of getting to surgery and achieving an R0!

We have these data from CM816. Return to baseline QoL occurs regardless of surgical access or extent of surgery. These are not really as relevant considerations as the importance of getting to surgery and achieving an R0!
Rafeeque Mavoor (@rafeequemavoor) 's Twitter Profile Photo

Free scientific illustrations for biologists! 😍 NIH has released a library of 500+ free scientific illustrations to create figures, presentations, and illustrations! all freely available in the public domain. Retweet and spread the message! bioart.niaid.nih.gov

Free scientific illustrations for biologists! 😍

<a href="/NIH/">NIH</a> has released a library of 500+ free scientific illustrations  to create figures, presentations, and illustrations!   

all freely available in the public domain. 

Retweet and spread the message!
bioart.niaid.nih.gov
Jordan Bloom (@jordanbloommd) 's Twitter Profile Photo

Over 50% of patients under 60 in California are getting TAVR. This is absurd! Huge shoutout to Jo Chikwe and team for exposing the alarming truth: TAVR has a 250% higher risk of death in 5 years compared to SAVR. annalsthoracicsurgery.org/article/S0003-…

NFL Films (@nflfilms) 's Twitter Profile Photo

.Josh Allen found the crease and trusted his feet. 💨 Uncharacteristic mistakes by the Chiefs' defense opened a running lane to victory. #NFLTurningPoint on ESPN+

Jonathan Spicer MD PhD (@doctorjspicer) 's Twitter Profile Photo

Curious to see how those periop vs neoadj debates go now that OS is positive for CM816! Excellent news for patients and health care systems! Congrats to the CM816 team brilliantly led by the wonderful ⁦Patrick Forde⁩!!! ⁦IASLC⁩ ⁦AATS⁩ news.bms.com/news/corporate…

Patrick Forde (@fordepatrick) 's Twitter Profile Photo

Reposting on day that it was announced neoadjuvant only chemo-nivolumab delivers a long term survival benefit in surgically resectable lung cancer, 3 doses of therapy (compared to potentially 16+ in other perioperative/adjuvant immunotherapy regimens) #lcsm

Drew Moghanaki (@drewmoghanaki) 's Twitter Profile Photo

1/ The Dutch ESLUNG study is potentially the largest prospective registry (n=2,183) evaluating outcomes for stage I NSCLC treated with minimally invasive surgery or SABR. Their non-randomized data, when propensity-matched, show similar findings to those previously reported by the

1/ The Dutch ESLUNG study is potentially the largest prospective registry (n=2,183) evaluating outcomes for stage I NSCLC treated with minimally invasive surgery or SABR. Their non-randomized data, when propensity-matched, show similar findings to those previously reported by the
Jeff Yang MD FACS (@chifujeffyang) 's Twitter Profile Photo

Dr. Linda Martin (Linda Martin) presented the surgical outcomes of the Alliance AFT-46 trial at #AATS2025. AFT-46 is chemo / durva followed by surgery for stage IIIA/IIIB N2 NSCLC. This is a really special study for our field — the rare investigator-initiated multi-center

Dr. Linda Martin (<a href="/LindaMThoracic/">Linda Martin</a>) presented the surgical outcomes of the Alliance AFT-46 trial at #AATS2025.  AFT-46 is chemo / durva followed by surgery for stage IIIA/IIIB N2 NSCLC. This is a really special study for our field — the rare investigator-initiated multi-center
Patrick Forde (@fordepatrick) 's Twitter Profile Photo

Remarkable results for neoadj chemo-immunotherapy in locally advanced, N2/N3, lung cancer. 75% curative resections w v high pCR. Notably >40% of pts treated had high PD-L1 (unselected would be ~25-30%) but the boundary for lung surgery continues to chase the horizon #LCSM

Shanda Blackmon, MD, MPH (@shandablackmon) 's Twitter Profile Photo

Our team BCM_Surgery BCM Cardiothoracic Surgery Residency The Lung Institute at Baylor Medicine BCMHouston at Baylor College of Medicine has been performing complex esophageal reconstruction to create GI continuity for patients with a multidisciplinary team that includes microvascular surgeons, vocal cord renervation

Our team <a href="/BCM_Surgery/">BCM_Surgery</a>  <a href="/BCM_CTSurgery/">BCM Cardiothoracic Surgery Residency</a> <a href="/BCMLungInst/">The Lung Institute at Baylor Medicine</a> <a href="/bcmhouston/">BCMHouston</a> at Baylor College of Medicine has been performing complex esophageal reconstruction to create GI continuity for patients with a multidisciplinary team that includes microvascular surgeons, vocal cord renervation
Jonathan Spicer MD PhD (@doctorjspicer) 's Twitter Profile Photo

Why is CM816 so important? After Patrick Forde beautiful presentation of these revolutionary data, let’s dig into why this unique trial should shake up our vision for oncology research…

Why is CM816 so important? After <a href="/FordePatrick/">Patrick Forde</a> beautiful presentation of these revolutionary data, let’s dig into why this unique trial should shake up our vision for oncology research…
Elliot Servais, MD, FACS (@elliotservaismd) 's Twitter Profile Photo

AIM-HIGH trial published in Lancet Molecular high-risk stage IA-IIA NSCLC as determined by 14-gene assay with improved survival with adjuvant chemo. It is not often we see survival curves like this in early stage lung cancer. thelancet.com/journals/lanre…

AIM-HIGH trial published in Lancet
Molecular high-risk stage IA-IIA NSCLC as determined by 14-gene assay with improved survival with adjuvant chemo.

It is not often we see survival curves like this in early stage lung cancer. 

thelancet.com/journals/lanre…
K. Patrick Seastedt, MD, FACS (@seastedtmd) 's Twitter Profile Photo

Excited to share our latest work presented at the AACR AI/ML 2025 conference in Montreal! 🌟 We developed a multimodal LLM-driven framework for precision risk prediction in lung cancer surgery, outperforming surgeons and model baselines with an AUC of 0.81. By fusing clinical,

Excited to share our latest work presented at the <a href="/AACR/">AACR</a>  AI/ML 2025 conference in Montreal! 🌟 We developed a multimodal LLM-driven framework for precision risk prediction in lung cancer surgery, outperforming surgeons and model baselines with an AUC of 0.81. By fusing clinical,