
Sebastian Roemer-Cassiano
@sebroemer
@sebroemer.bsky.social
Clinician Scientist at Franzmeier-Lab ISD; Resident Physician in Neurology at LMU Munich; Max Planck School of Cognition PhD
ID: 1187202307
16-02-2013 19:20:48
65 Tweet
126 Followers
201 Following


Happy to share Davina Biel newest in EMBO Mol. Medicine showing stronger Aβ-dependent p-tau increases in women, potentially driven by elevated sTREM2-related microglial activation and stronger effects of ApoE4 carriership in women Many thanks also to MatthiasBrendel! doi.org/10.1038/s44321…


Happy to share our new preprint led by Johannes Sebastian Gnörich and MatthiasBrendel, showcasing a full ATN staging approach using a single dynamic PI-2620 scan, leveraging advanced kinetic modelling techniques medrxiv.org/content/10.110…


Always my favourite post at the beginning of the year: Registration for our course “Biomarkers for neurodegenerative diseases” is now open! This year’s edition takes place at UCL Queen Square Institute of Neurology in central London on May 12-16. biomarker-course.org



Nice to see Alzforum covering our most recent article in Science Translational Medicine and highlighting its importance for future lines of research and therapy! Special thanks David Jones and Tarick Pascoal for the great comments on our work! alzforum.org/news/research-…


What’s the relationship between #AmyloidBeta and tau protein? New research involving #AlzheimersDisease patient PET and fMRI data reveals amyloid-beta may drive tau spread through hyperconnectivity between vulnerable brain regions. Nico Franzmeier Sebastian Roemer-Cassiano scim.ag/3CfY6aR


Thanks to Nat Rev Neurology for highlighting our latest work on amyloid-induced hyperconnectivity and how it promotes tau spread! Can’t wait for the next studies to describe this novel mechanism more in detail and maybe even tackle it therapeutically!? Exciting times


de Bruin et al. report that traumatic brain injury alters amyloid-β and tau deposition, with increased accumulation in fronto-parietal regions, & disrupts amyloid-tau coupling. Please read at: buff.ly/437ElwX Hannah de Bruin Colin Groot RikOssenkoppele Nico Franzmeier


Many thanks to the ADPD2025 committee for recognizing our work with Nico Franzmeier on the effects of amyloid-induced hyperconnectivity on tau spreading! If you are enjoying a Gösser Radler and a Sacher Torte in Vienna, don't miss ADPD and my talk in Hall C at 10:00 on Wed 02.04.25




