Sebastian Roemer-Cassiano (@sebroemer) 's Twitter Profile
Sebastian Roemer-Cassiano

@sebroemer

@sebroemer.bsky.social
Clinician Scientist at Franzmeier-Lab ISD; Resident Physician in Neurology at LMU Munich; Max Planck School of Cognition PhD

ID: 1187202307

calendar_today16-02-2013 19:20:48

65 Tweet

126 Followers

201 Following

Nico Franzmeier (@nfranzme) 's Twitter Profile Photo

Paper alert: We performed a prognostic validation of the MDS PSP criteria, showing most patients with possible/suggestive PSP show an increase in diagnostic certainty over time. Increase in diagnostic certainty could be used as an endpoint in trials doi.org/10.1002/mds.30…

Paper alert: We performed a prognostic validation of the MDS  PSP criteria, showing most patients with possible/suggestive PSP show an increase in diagnostic certainty over time. Increase in diagnostic certainty could be used as an endpoint in trials 
doi.org/10.1002/mds.30…
Nico Franzmeier (@nfranzme) 's Twitter Profile Photo

Happy to share Davina Biel newest in EMBO Mol. Medicine showing stronger Aβ-dependent p-tau increases in women, potentially driven by elevated sTREM2-related microglial activation and stronger effects of ApoE4 carriership in women Many thanks also to MatthiasBrendel! doi.org/10.1038/s44321…

Happy to share <a href="/davinabiel/">Davina Biel</a> newest in <a href="/EmboMolMed/">EMBO Mol. Medicine</a> showing stronger Aβ-dependent p-tau increases in women, potentially driven by elevated sTREM2-related microglial activation and stronger effects of ApoE4 carriership in women
Many thanks also to <a href="/matbrendel/">MatthiasBrendel</a>! doi.org/10.1038/s44321…
Nico Franzmeier (@nfranzme) 's Twitter Profile Photo

Happy to share our new preprint led by Johannes Sebastian Gnörich and MatthiasBrendel, showcasing a full ATN staging approach using a single dynamic PI-2620 scan, leveraging advanced kinetic modelling techniques medrxiv.org/content/10.110…

Happy to share our new preprint led by <a href="/JGnorich/">Johannes Sebastian Gnörich</a> and <a href="/matbrendel/">MatthiasBrendel</a>, showcasing a full ATN staging approach using a single dynamic PI-2620 scan, leveraging advanced kinetic modelling techniques

medrxiv.org/content/10.110…
Michael Schöll (@_michael_scholl) 's Twitter Profile Photo

Always my favourite post at the beginning of the year: Registration for our course “Biomarkers for neurodegenerative diseases” is now open! This year’s edition takes place at UCL Queen Square Institute of Neurology in central London on May 12-16. biomarker-course.org

Science Translational Medicine (@sciencetm) 's Twitter Profile Photo

This week's issue of #ScienceTranslationalMedicine is out now! A new transplant protocol extends the survival of heart transplants in large animals, researchers explore emerging horizons in the use of hypoxia to treat chronic conditions, and more. scim.ag/3EiZjhW

This week's issue of #ScienceTranslationalMedicine is out now! 

A new transplant protocol extends the survival of heart transplants in large animals, researchers explore emerging horizons in the use of hypoxia to treat chronic conditions, and more. scim.ag/3EiZjhW
Sebastian Roemer-Cassiano (@sebroemer) 's Twitter Profile Photo

Nice to see Alzforum covering our most recent article in Science Translational Medicine and highlighting its importance for future lines of research and therapy! Special thanks David Jones and Tarick Pascoal for the great comments on our work! alzforum.org/news/research-…

Nice to see <a href="/alzforum/">Alzforum</a> covering our most recent article in <a href="/ScienceTM/">Science Translational Medicine</a> and highlighting its importance for future lines of research and therapy! Special thanks <a href="/DavidJonesBrain/">David Jones</a> and Tarick Pascoal for the great comments on our work!

alzforum.org/news/research-…
Science Translational Medicine (@sciencetm) 's Twitter Profile Photo

What’s the relationship between #AmyloidBeta and tau protein? New research involving #AlzheimersDisease patient PET and fMRI data reveals amyloid-beta may drive tau spread through hyperconnectivity between vulnerable brain regions. Nico Franzmeier Sebastian Roemer-Cassiano scim.ag/3CfY6aR

What’s the relationship between #AmyloidBeta and tau protein? 

New research involving #AlzheimersDisease patient PET and fMRI data reveals amyloid-beta may drive tau spread through hyperconnectivity between vulnerable brain regions. <a href="/nfranzme/">Nico Franzmeier</a> <a href="/SebRoemer/">Sebastian Roemer-Cassiano</a> scim.ag/3CfY6aR
Sebastian Roemer-Cassiano (@sebroemer) 's Twitter Profile Photo

Thanks to Nat Rev Neurology for highlighting our latest work on amyloid-induced hyperconnectivity and how it promotes tau spread! Can’t wait for the next studies to describe this novel mechanism more in detail and maybe even tackle it therapeutically!? Exciting times

Sebastian Roemer-Cassiano (@sebroemer) 's Twitter Profile Photo

Paradox to post this on this platform, but in case you want to know what's going on in Germany and how 20% of the population seem to be able to live everyday life without a brain: youtu.be/bLWLb0RM7HQ?si…

@BrainComms (@braincomms) 's Twitter Profile Photo

de Bruin et al. report that traumatic brain injury alters amyloid-β and tau deposition, with increased accumulation in fronto-parietal regions, & disrupts amyloid-tau coupling. Please read at: buff.ly/437ElwX Hannah de Bruin Colin Groot RikOssenkoppele Nico Franzmeier

de Bruin et al. report that traumatic brain injury alters amyloid-β and tau deposition, with increased accumulation in fronto-parietal regions, &amp; disrupts amyloid-tau coupling. Please read at: buff.ly/437ElwX <a href="/deBruin_Hannah/">Hannah de Bruin</a> <a href="/Colin__Groot/">Colin Groot</a> <a href="/RikOssenkoppele/">RikOssenkoppele</a> <a href="/nfranzme/">Nico Franzmeier</a>
Sebastian Roemer-Cassiano (@sebroemer) 's Twitter Profile Photo

Many thanks to the ADPD2025 committee for recognizing our work with Nico Franzmeier on the effects of amyloid-induced hyperconnectivity on tau spreading! If you are enjoying a Gösser Radler and a Sacher Torte in Vienna, don't miss ADPD and my talk in Hall C at 10:00 on Wed 02.04.25

Many thanks to the ADPD2025 committee for recognizing our work with <a href="/nfranzme/">Nico Franzmeier</a> on the effects of amyloid-induced hyperconnectivity on tau spreading! If you are enjoying a Gösser Radler and a Sacher Torte in Vienna, don't miss ADPD and my talk in Hall C at 10:00 on Wed 02.04.25
Nico Franzmeier (@nfranzme) 's Twitter Profile Photo

Excited to share our new work in Molecular Neurodegeneration, showing that α-synuclein co-pathology is common in Alzheimer’s and accelerates amyloid-related tau accumulation, supporting its role as a tau co-aggregation factor. doi.org/10.1186/s13024…

Emma Coomans (@emmacoomans) 's Twitter Profile Photo

So excited and honored to be invited to present the opening plenary at #AIC2025 this year in Toronto! 🧠 🙏 I would be very grateful if you could help me gather the most inspiring papers (including your own!) of the past year by completing this survey: alz.surveymonkey.com/r/923BTQK

Nico Franzmeier (@nfranzme) 's Twitter Profile Photo

Happy to share new work by Carla Palleis in MDS, showing that brain networks route neurodegeneration patterns in PSP => This suggests that grey matter atrophy expands across connected brain regions, potentially following tau accumulation in PSP doi.org/10.1002/mds.30…

Happy to share new work by Carla Palleis in <a href="/movedisorder/">MDS</a>, showing that brain networks route neurodegeneration patterns in PSP
=&gt; This suggests that grey matter atrophy expands across connected brain regions, potentially following tau accumulation in PSP

doi.org/10.1002/mds.30…
Nico Franzmeier (@nfranzme) 's Twitter Profile Photo

Very happy to share our 2nd paper today, led by Lukas Frontzkowski: We developed a novel data driven reference region for PI-2620 PET tailored to assess 4R tauopathies, improving i) PSP vs. control separation and ii) PET associations with clinical scores doi.org/10.1007/s00259…

Very happy to share our 2nd paper today, led by Lukas Frontzkowski: We developed a novel data driven reference region for PI-2620 PET tailored to assess 4R tauopathies, improving i) PSP vs. control separation and  ii) PET associations with clinical scores
doi.org/10.1007/s00259…