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‘The Year of Our Lorde 1665 hath been such a terrible one for ye plague. I cannot wait for 1666, for which I have especial excitement to trye the newe bakery that hath opened on Pudding Lane.’ Samuel Pepys, Diary Entry, 31 December 1665.

Dear EU So long and thanks for all the fish... X

We are in talks with the Government about using our closed BrewDog bars as vaccination centres. We are also going to give everyone who gets vaccinated at a BrewDog bar a special commemorative beer. But what should we call it?

The power of in vitro reconstitution to understand biochemistry 😍

An mRNA HIV vaccine looks promising in primates ... seems the dawn of a new era 😲

Our first 2021 paper reveals the prevalence and mechanism of a co-translational protein assembly mechanism in human cells: co-co assembly. Congratulations to the co-co team Kai Fenzl, @matildebertolin and @guenter_kramer! science.sciencemag.org/content/371/65… @Sciart by Marzia Munafò 1/6

In the beginning... Miescher's "Nuclein" extract First chromatin prep #ChromatinHaiku #1871

Beautiful work and also an illustration of why the truly physiologically relevant protein folding problem needs to be studied in the cellular context.

For the first time in its history, Cambridge Market. has been shut down and barricaded - coincidentally on the day of Brexit 'freedom and sovereignty'. I can't think of more ironic metaphor.

JUST BE CLEAR! EPIGENETIC HULK NOT LADY WISTLEDOWN!

Sadly 1666 was the year when the great fire of London started exactly in the bakery in Pudding Lane ... just a reminder for those placing too much hope on 2021 😬

Some of the reporting by the media really has been atrocious. Instead of trying to help they seem more intent on stirring up an inaccurate story. BMJ urges NYT to correct vaccine 'mixing' article bbc.co.uk/news/uk-555190…

A rather gloomy start of 2021 in Cambridge 😢 Mask up 😷. Stay safe, help end this pandemic !

Enormous snow flakes coming down in Northumberland, England today! Who else could watch this all day? 🎥 @deborahparkin x.com/deborahparkin/…

I tell you what, you don't hear Boris Johnson and Matt Hancock talking about the £22bn Serco Test and Trace system as the way to control the virus anymore do you?

Two days left to apply for this program! Come to Oxford to train as a structural biologist....exciting projects, great facilities, outstanding colleagues and supervisors, generous support from Wellcome. Why would you not apply?!

We are excited to share our Science Magazine study on RNA triple helices led by Seyed Torabi! Here we describe the structure of an RNA element that protects the poly(A) tail through the formation of a 3ʹ-end binding pocket and other RNA interactions. science.sciencemag.org/content/early/…

Beautiful work from Joan Steitz Lab - I remember hearing about this intriguing mechanism of RNA stabilisation after my seminar at Yale last year; very nice to see this published

Cambridge Lockdown v3 - the winter, unfortunately more scary, edition 😬

We found a welcoming journal home for our work explaining how the spliceosome toggles between competing conformations during splicing catalysis sciencedirect.com/science/articl…