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Very pleased our paper iHerd: an integrative hierarchical graph representation learning framework to quantify network changes and prioritize risk genes in disease out in ⁦PLOS Comp Biol⁩. With ⁦JingZhang⁩ ⁦Yale Psychiatry⁩ journals.plos.org/ploscompbiol/a…

R21 funded by NIAAA with Marianne Seney and Ryan Logan! Investigating molecular rhythm disruptions in alcohol use disorder. Excited to start! NIAAA News Pitt Psychiatry

Check out our paper in Cell Reports !

So excited about our new work which explains how VGLUT protects #dopamine neurons in males vs females in #Parkinsons. Huge achievement by Silas Buck and amazing colleagues! Ryan Logan Scott Waddell liefefenno Marianne Seney @NIEHS Pitt Psychiatry biorxiv.org/content/10.110…

Welcome, CNUP 1st years of 2023! 🎉

Goodbye #ACNP2023 Thanks for the memories. Already excited for next year!

Our newest pub! snRNAseq in human and non-human primate brain reveals elevated DNA damage markers in striatum related to chronic opioid use. Led by Dr. Maddie Ray and @BaDoiPhan.bsky.social. Collaboration with Andreas Pfenning and others. Excited to have this out! nature.com/articles/s4146…

If attending Society for Research on Biological Rhythms meeting in May, please register for the Junior Faculty Workshop. A fantastic program slated for afternoon. Thank you to everyone who volunteered to participate! Any questions, get at me. #sleep #circadian #SRBR2024 srbr.org/srbr-junior-fa…

Greetings from Toronto! Many thanks to Dr. Liisa Galea and Iva Zovkic @ivazovkic.bsky.social for such warm welcome! Having a great time w/ Cognitive Neuroendocrinology Dr. Kristen Zuloaga Katie Morrison Marianne Seney @GeorgiaHodes .. Looking forward to the conference! #WomensMentalHealth

What a great line-up of speakers and wonderful company here at #womenmind24 .. Enjoying this woman power working together to improve #WomensMentalHealth ! Dr. Liisa Galea Cognitive Neuroendocrinology Emily G. Jacobs 🦋 @emilyjacobs.bsky.social Dr. Kristen Zuloaga Katie Morrison Marianne Seney @GeorgiaHodes

A huge congrats to Geert de Vries, winner of the Daniel S. Lehrman Lifetime Achievement Award! 🥳 Geert's work on sex differences and vasopressin innervation has shaped the field, while his commitment to mentorship and service has ensured a lasting legacy.

Congrats to Carly Fabian, Max Joffe, and team. It’s fun working with friends!

.Mary Torregrossa and I are thrilled to announce that we are directing a new NIDA funded postdoctoral T32 at University of Pittsburgh! If anyone is interested in a postdoc in addiction-related research with one of our amazing faculty please send a DM. Slots available starting July 1.

Really excited about this new R01 from NIDA with Kyle Ketchesin and Mary Torregrossa! NIDAnews Pitt Psychiatry

Please reach out to us if you are interested in doing a postdoc in research related to substance use disorders! Pittsburgh is a wonderful place to train with fantastic faculty doing basic, translational and clinical research.

It’s NGA day!! New R01 with Ryan Logan !!! Pitt Psychiatry

Sex-specific Concordance of Striatal Transcriptional Signatures of Opioid Addiction in Human and Rodent Brains New preprint, definition of work in progress, where we compare opioid induced transcript alterations in cortical and striatal brain regions across mice, heterogeneous

Please see this exciting publication by Philipp Mews and others which describes a novel "chromatin scar" induced by cocaine, lasting depletion of H2A.Z from nucleosomes, in nucleus accumbens medium spiny neurons that drives gene priming and drug relapse. science.org/doi/10.1126/sc…

Big congrats to Carly Fabian !!!

Just because you don't see a sex difference in your behaviour does not mean you will not see sex differences in mechanism. NB there are different types of sex differences and mechanistic sex differences will mean different treatments are likely needed to modify the behaviour.