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Screening colonoscopy (M, 68y.o.) Location - cecum Size ~ 18mm Morphology: Paris 0-IIa type (LST-G) Pit pattern – IIIL NBI – JNET2A Optical diagnosis: tubular adenoma with LGD Treatment – endoscopic mucosal resection (EMR) Pathology report – tubular adenoma LGD (ICD-O code:

Endometriosis is a condition in which pieces of the uterine tissue grow outside of the uterus. There are different types of endometriosis, as the condition can occur in different parts of the body. In some cases, endometrial tissue grows on or inside the intestines. This is

The light blue crest (LBC), a blue-whitish patchy area observable with NBI-magnification endoscopy on the gastric epithelial surface, may have a distinctive endoscopic diagnostic appearance of intestinal metaplasia.

Screening colonoscopy (F, 76y.o.) Location – ascending colon Size ~20mm Morphology: 0-ІIa Pit pattern – II+IIO NBI – JNET1 Optical diagnosis: Sessile serrated lesion (SSL) Treatment – Piecemeal cold snare polypectomy (CSP) Pathology report - Sessile serrated lesion

Screening colonoscopy (F, 69y.o.) Location - sigmoid colon Size ~ 5mm Morphology: 0-ІIa Pit pattern – IIIL+IIIs NBI - JNET2A Optical diagnosis: tubular adenoma with LGD Treatment - cold snare polypectomy (CSP) Pathology report - tubular adenoma LGD (ICD-O code: 8211/0). No signs

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Screening colonoscopy (M, 66y.o.) Location - cecum Size ~ 4mm Morphology: Paris 0-IIa type (flat elevation of mucosa) Pit pattern – IIIL NBI – JNET2A Optical diagnosis: tubular adenoma with LGD Treatment – cold snare polypectomy (CSP) Pathology report – tubular adenoma LGD

Colonoscopy case: inflammatory bowel disease (IBD)- Ulcerative colitis with Inflammatory polyp

Screening colonoscopy (M, 66y.o.) Location - transverse colon Size ~ 6mm Morphology: Paris 0-IIa type (flat elevation of mucosa) Pit pattern – IIIL NBI – JNET2A Optical diagnosis: tubular adenoma with LGD Treatment – cold snare polypectomy (CSP) Pathology report – tubular

Endoscopic view of the terminal ileum

Screening colonoscopy (M, 53y.o.) Location - ascending colon Size ~ 5mm Morphology: Paris 0-IIa type (flat elevation of mucosa) Pit pattern – IIIL NBI – JNET2A Optical diagnosis: tubular adenoma with LGD Treatment – cold snare polypectomy (CSP) Pathology report – tubular

Colonoscopy case (M, 72y.o.) Follow-up colonoscopy (after previous colonoscopy 5 years ago with polypectomy) Location - transverse colon Size ~ 14mm Morphology: Paris 0-IIa type (flat elevation of mucosa) Pit pattern – IIIL NBI – JNET2A Optical diagnosis: tubular adenoma with

Colonoscopy case (F, 49y.o.) Location - anal canal Endoscopic view of Anal High-Grade Squamous Intraepithelial Lesion (HSIL)

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Should endoscopists learn histopathological correlation? I believe so, as my own experience has greatly enhanced my understanding of optical diagnosis during colonoscopy. Screening colonoscopy (F,48y.o.) Location - upper rectum Size ~ 12mm Morphology: Paris 0-Is+IIa type Pit

Colonoscopy case (F,48y.o.) Medical history: rectal bleeding Location - upper rectum Size ~45mm Morphology: Paris 0-Is type (lst-g) Pit pattern – IV+Vi NBI – JNET 2A + JNET 2B-low Optical diagnosis: Villous adenoma with HGD Treatment – Endoscopic Submucosal Dissection (ESD)

Colonoscopy case (F, 66y.o.) - Screening colonoscopy Location - transverse colon Size ~ 3mm Morphology: Paris 0-IIa type (flat elevation of mucosa) Pit pattern – IIIL NBI – JNET2A Optical diagnosis: tubular adenoma with LGD Treatment – cold snare polypectomy (CSP) Pathology

Colonoscopy case (M, 21 y.o.) - diagnostic colonoscopy (diarrhea) Location - sigmoid colon, rectum Endoscopic signs of ulcerative colitis (UC) Endoscopic classification of IBD: Mayo score - 2 UCEIS V (Vascular pattern) - 1 UCEIS B (Bleeding) - 1 UCEIS E (Erosion and ulcers) - 1

This video was created using AI technologies and is for informational purposes only. Its goal is to draw attention to important aspects concerning colonoscopy and the problem of colorectal cancer. The materials presented in this video are based on publicly available information