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Thanks to Chemistry at Thieme for featuring our recent work on SpiroCyclobutyl-substituted Dioxetane Chemiluminophores in Synfacts! thieme-connect.com/products/ejour…

Today we report in J. Am. Chem. Soc. a novel and highly modular platform for mechanically triggered chemiluminescence (bright light emission) from polymers. Congrats to Peng Liu｜刘朋, Yu-Ling (Debbie), and coworkers! Collab with Shabat Group. Caltech Chemistry & Chemical Engineering Caltech pubs.acs.org/doi/10.1021/ja…

The final version of this Preprint has been published today in Angewandte Chemie: onlinelibrary.wiley.com/doi/10.1002/an…

"Biocompatible Flash Chemiluminescent Assay Enabled by Sterically Hindered Spiro-Strained-Oxetanyl-1,2-Dioxetane" Productive collaboration with Ronit Satchi-Fainaro, Micha Fridman and Biosynth Appearing today in ChemRxiv: chemrxiv.org/engage/chemrxi…

The final version of this work was published in JACS Au: pubs.acs.org/doi/10.1021/ja…

The FIRST chemiluminescent probe with a Turn-ON mechanism, utilizing a PeT mode-of-action. Insightful collaboration with Muhammad Jbara: Appearing today in ChemRxiv: chemrxiv.org/engage/chemrxi…

Chemiexcitation Acceleration of 1,2-Dioxetanes by Spiro-Fused Six-Member Rings with Electron-Withdrawing Motifs (Doron Shabat and co-workers) Shabat Group #openaccess #AngewandteVIP onlinelibrary.wiley.com/doi/10.1002/an…

“Thymidine Phosphodiester Chemiluminescent Probe for Sensitive and Selective Detection of Ectonucleotide Pyrophosphatase 1”. Inspiring collaboration with Baran Lab, Appearing today in ChemRxiv: chemrxiv.org/engage/chemrxi…

The final version of this work was published today in Angewandte Chemie: onlinelibrary.wiley.com/doi/10.1002/an… Many thanks to Muhammad Jbara for the team effort.

Finally, RADICAL CROSS COUPLING without the exogenous REDOX. We disclose in ChemRxiv (chemrxiv.org/engage/chemrxi…) a broadly general platform for achieving transformations that normally required excess metallic or chemical reducing agents or photochemical setups (and their

You don't need to be a chemist to make C(sp3)-C(sp2) bonds... (video by Tamara E)

“Structure-Activity Optimization of Phenoxy-1,2-Dioxetane Precursors as Probes for Singlet Oxygen Yields Unprecedented Detection Sensitivity”, Appearing now in ChemRxiv: chemrxiv.org/engage/chemrxi…

The final version of this manuscript was published in Bioconjugate Chem: pubs.acs.org/doi/10.1021/ac…. Many thanks to Baran Lab and Ronit Satchi-Fainaro for this fruitful collaboration.

Big thanks to Derek Lowe for the thoughtful commentary on our manuscript! Your insights on antifungal research and the challenges we face in drug discovery are invaluable. What the Antifungals Are Really Doing | Science | AAAS science.org/content/blog-p…

🚨RADICAL RETHINK: STEREORETENTIVE CROSS COUPLING UNLOCKED🚨 Today in ChemRxiv (chemrxiv.org/engage/chemrxi…) the first method for stereoretentive radical cross-coupling is disclosed. No fancy ligands or redox needed—just a Ni-diazene twist. 120 years after Gomberg, a new chapter

Appearing today in nature : nature.com/articles/s4158…

The First Caspase-3 Chemiluminescent Probe. Appearing today in Bioconjugate Chemistry: pubs.acs.org/doi/full/10.10…

Our latest paper is now out in J. Am. Chem. Soc. ! We unveil a new strategy to access elusive free oxoboranes—highly reactive species—via bridged boranoanthracenes and aromatization-driven extrusion. Congratulations to the team! pubs.acs.org/doi/10.1021/ja…

The final version of this manuscript was published in JACS Au: pubs.acs.org/doi/10.1021/ja…

Just introduced: Phenylamine-1,2-Dioxetanes - a powerful revived class of chemiluminescent luminophores with high quantum yield and exceptional performance in aqueous bioassays. No enhancers needed. Today in ChemRxiv (chemrxiv.org/engage/chemrxi…)