We are happy to share our recent work hot off the press! With a wonderful collaboration with Dr. Ji Zhu, in a phase III clinical study, we identified key responsive metabolic traits over the course of neoadjuvant chemoradiotherapy for patients with LARC. nature.com/articles/s4146…

Very happy to share our latest review article. sciencedirect.com/science/articl…

Happy to share our new work. We develop a mass spectrum-oriented bottom-up assembly algorithm Met4DX for ion mobility-resolved metabolomics. Congrats the Team! doi.org/10.1038/s41467…

Happy to share our new work in which we developed MetImage to encode LC–MS-based untargeted metabolomics data into multi-channel digital images towards clinical diagnosis. pubs.acs.org/doi/abs/10.102…

Hot off the press😀My group started constructing a database for CCS values of small molecular compounds in 2015. After eight years and three generations of development, the AllCCS database has become increasingly mature. We welcome everyone to use it. 🙌pubs.acs.org/doi/10.1021/ac…

What a wonderful ZhuLab 10th Anniversary party!👏👏👍😀😊🤗🤗🤗 Thanks so much all former and current members. Looking forward to the next 10, 20... years🤗

We are so exciting that Prof. Matej Oresic flies to China as our plenary speaker for the 3nd Annual Conference for the Chiniese Society of Metabomics! What a wonderful presentation on microbiome, bile acids, and exposome for up to 800 attendees👏👏👏 Thank you, Prof. Oresic!

Thank you so much, Prof. Oresic! It is our fortune to have the opportunity to invite you to deliver an excellent presentation here in China. Hope you had a great time with us🤗🤗

Delighted to share our great collaboration! Using MetDNA(metdna.zhulab.cn), we found intestinal phenylethylamine promotes the susceptibility of female mice to multiple sclerosis and N2-acetyl-L-lysine inhibits neuroinflammation during the disease. doi.org/10.1016/j.immu…

What a amazing work! Huge congratulations, Pieter!👏 Pieter Dorrestein

Excellent lineup of invited speakers at #NMetC2024 Tomáš Pluskal María Eugenia Monge ZhuLab_Shanghai Jingyuan Fu Ottarr Rolfsson Dr Ana Rodriguez-Mateos Maaria Kortesniemi Egon Willighagen Majority of talks selected from abstracts (WWW pages opening soon). Conf. dinner in Turku castle.

Looking forward to presenting at the 4th Nordic #Metabolomics Conference #NMetC2024

Happy to share our collobrative work which identified that lysophosphatidylcholine (LPC) binds α-synuclein and prevents its pathological aggregation academic.oup.com/nsr/advance-ar…

Happy to share our work with Prof. Xu. We used sterolomics technology and identified cholesterol metabolites shapes immune landscape of colorectal cancer embopress.org/doi/full/10.10…

Application scenarios using MetDNA2

Met4DX supports data processing of both 3-dimensional LC-MS data and 4-dimensional LC-IM-MS data. Welcome to use! met4dx.zhulab.cn

Happy to share our collobrative work with Prof. Junying Yuan which identified that metabolite spermidine mediates acetylhypusination of RIPK1 to suppress diabetes onset and progression doi.org/10.1038/s41556…

Finally out! Happy to share our work Science Advances . We elucidate that citrulline served as a potential inhibitor of mTOR activation in macrophage and regulated the mTOR–HIF 1α–glycolysis signaling pathway to counter inflammation and aging.science.org/doi/10.1126/sc…

Happy to share our work IsoNet. Using mass spectrometry-resolved stable-isotope tracing metabolomics, we develop an isotopologue similarity networking strategy to effectively deduce previously unknown metabolic reactions. nature.com/articles/s4146…

Another work on in vivo stable-isotope tracing metabolomics. We revealed tissue-specific fatty acid biosynthesis and inter-tissue crosstalk in mice through mass spectrometry-resolved stable-isotope tracing metabolomics. advanced.onlinelibrary.wiley.com/doi/10.1002/ad…