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Liquid-like transcription condensates locally constrain chromatin in living human cells biorxiv.org/content/10.110…

Glymphatic dysfunction in Alzheimer’s disease: A critical appraisal | Science science.org/doi/10.1126/sc…

PRMT5 activity sustains histone production to maintain genome integrity biorxiv.org/content/10.110…

Microglia replacement halts the progression of microgliopathy in mice and humans | Science science.org/doi/10.1126/sc…

Replacing microglia to treat a brain disease | Science science.org/doi/10.1126/sc…

Tissue-integrated bionic knee restores versatile legged movement after amputation | Science science.org/doi/10.1126/sc…

Integrated prostheses restore dynamic movement | Science science.org/doi/10.1126/sc…

ROS transfer at peroxisome-mitochondria contact regulates mitochondrial redox | Science science.org/doi/10.1126/sc…

Organelles share the load | Science science.org/doi/10.1126/sc…

The biophysical requirements that govern the efficient endosomal escape of designed mini-proteins: nature.com/articles/s4155…

Molecular recording of cellular protein kinase activity with chemical labeling: nature.com/articles/s4158…

Intersectin and endophilin condensates prime synaptic vesicles for release site replenishment: nature.com/articles/s4159…

ft. D. Amado (University of Pennsylvania Neurology), Ashley Brooke Robbins, K. Whiteman, A. Smith, Guillem Chillon, Y. Chen, J. Fuller, Nick Patty, A. Izda, C. Cheng, S. Nelson, A. Dichter, A. Mas Monteys & DAVIDSON LAB (CHOP Research) Penn Path & Lab Medicine nature.com/articles/s4146…

Structural basis for a nucleoporin exportin complex between RanBP2, SUMO1-RanGAP1, the E2 Ubc9, Crm1 and the Ran GTPase: nature.com/articles/s4146…

Chromatin heterogeneity modulates nuclear condensate dynamics and phase behavior: nature.com/articles/s4146…

The UBE3A-ATS antisense oligonucleotide rugonersen in children with Angelman syndrome: a phase 1 trial: nature.com/articles/s4159…

A heterotrimeric protein complex assembles the metazoan V-ATPase upon dissipation of proton gradients: nature.com/articles/s4159…

V-ATPase assembly at leaky lysosomes: nature.com/articles/s4159…

KIF5A downregulation in spinal muscular atrophy links axonal regeneration defects with ALS biorxiv.org/content/10.110…

Architectural RNAs: blueprints for functional membraneless organelle assembly: Trends in Genetics cell.com/trends/genetic…