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AHA Science AHAMeetings Cardiovascular disease is still a leading cause of death in the US. Clinicians and researchers should move toward framing CVD as a life-long disease -- not "cured" by stents and surgeries

#EPILifestyle23 opening session is today! Dr. Michelle A. Albert is giving the presidential remarks on implementing scientific knowledge for healthy hearts. AHAMeetings American Heart Association

Over 600 poster presentations, 13 moderated poster sessions, and daily networking roundtable session are happening at the #EPILifestyle23

#EPILifesyle23 Dr. Crystal Wiley Cené gave us a fun and informative keynote lecture on distinguishing, evaluating, and conducting implementation research, as well as the importance of leveraging implementation science among marginalized populations. Crystal Cené, MD, MPH AHAMeetings

Next up is Dr. Josiemer Mattei giving us examples of implementation of heart health science in the real world

#EPILifesyle23 Dr. Josiemer Mattei gave us an important keynote lecture on implementing evidence-based diet programs for minority groups, specifically her research on the cardiovascular health impacts of a Puerto Rico-optimized Mediterranean-like diet. American Heart Association

#EPILifesyle23 Dr. Sara Bleich gave us an excellent keynote lecture on the current nutrition policy in the U.S.! She introduced us to the many emerging opportunities to contribute to policy implementation and emphasized the value of clear communication. American Heart Association Dr. Sara Bleich

Tiange Tiange Liu, PhD, MBBS just presented their exciting finding that Infant Gut Microbiome Is Associated with Child Blood Pressure at Age 3 and 6 years in A Danish Birth Cohort. The association can be modified by breastfeeding duration. #EPILifestyle23 #JAHA_MeetingReport JAHA

Dr. Siwen Wang is giving a presentation on"Adherence to Preconception Healthy Lifestyle and Adverse Pregnancy Outcomes". They found Adherence to six healthy lifestyles is associated with lower risk of APO. #EPILifestyle23 JAHA AHAMeetings AHA Science #AHAJournals

Dr.Mingyu Z gave a fantastic talk on the long-lasting adverse effects of prenatal exposures to “forever chemicals” #PFAS on adiposity in childhood. This important work was done in Project Viva #EPILifestyle23

Dr. Powell-Wiley gave us two reasons why Pharmacotherapy should be prioritized: 1. Achieving and maintaining weight loss is challenging. 2. Lifestyle intervention is limited for those who are mostly affected by obesity #EPILifestyle24 #JAHAMeetingReport #AHAJournals JAHA

Evidence is accumulating for use of GLP1-RA for obesity and CVD treatment #EPILifestyle24 #JAHAMeetingReport #AHAJournals JAHA

Dr. Molly Baldwin Conroy: lifestyle and physical activity changes are still relevant topics for every patient and there are many opportunities in a primary care setting for lifestyle intervention. #EPILifestyle24 #JAHAMeetingReport #AHAJournals JAHA

Also "DPP-based lifestyle interventions are readily scalable and exportable with the potential for substantial clinical and public health impact"

Final point: there are already disparities in prescribing of pharmacotherapy, which could exacerbate disparities in outcomes #EPILifestyle24

GLP-1 RAs health benefits are more than just weight reduction. And its mental health side effects are unclear. #EPILifestyle24 #JAHAMeetingReport #AHAJournals JAHA

Rebuttal from Dr. Molly Baldwin Conroy: preliminary study shows a combination of lifestyle and pharmacotherapy treatment is better than pharmacotherapy alone in maintaining weight loss. #EPILifestyle24 #JAHAMeetingReport #AHAJournals JAHA

Lifestyle interventions should still be considered the foundation of first-line therapy for obesity.

Q: What do we know about GLP-1 weight loss effects on body composition? A.: Potential concerns for lean muscle mass loss (e.g. sarcopenia), more research is needed. Types of physical activity combined with pharmacotherapy are important (e.g., resistance training).

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