
Simon Woelfel
@simonwoelfel
PhD student in the Stecher lab @LMU_Muenchen. Interested in bacterial evolution, inflammatory diseases, and all things microbiome.
ID: 1586994704624877569
31-10-2022 08:13:26
143 Tweet
95 Followers
231 Following




Please RT, because we are all „Born to be Wild“ and it really is time to think about reproducibility in biomedical research! A big THANK YOU to the brilliant Philipp Bruno and Thomas Schüler! Trends in Immunology Cell Press #wildlings buff.ly/2ZqIqc5 FAU Erlangen-Nbg Joachim Hornegger #HTA

Intestinal E. coli-produced yersiniabactin promotes profibrotic macrophages in Crohn’s disease cell.com/cell-host-micr… Cell Host & Microbe Janelle Arthur


The gut microbiome signature from different diets in >20,000 individuals. Red meat intake correlated with reduced cardiometabolic health; the opposite for plant-based foods or in omnivores with enriched plant-based intake nature.com/articles/s4156… Nature Microbiology Nicola Segata



Yersiniabactin promotes profibrotic macrophages in Crohn’s E. coli yersiniabactin sequesters zinc & stabilizes HIF-1α in macrophages, promoting profibrotic gene expression. HIF-1α+ Macs are abundant in fibrotic strictures of CD patients Janelle Arthur cell.com/cell-host-micr…


Please retweet. We are honored with the cover of Jan 2025 issue Trends in Immunology dlvr.it/TGqWwm! We are all „Born to be Wild“! cell.com/trends/immunol… Cell Press #wildlings buff.ly/2ZqIqc5 scim.ag/4hX FAU Erlangen-Nbg Joachim Hornegger #HTA

What a pleasure to see our bacterial-MERFISH work out in Science Magazine this week! Congratulations to the talented team that led this effort--Ari, Yuanyou, and Nana! science.org/doi/abs/10.112….



IBD-associated small molecules Moamen Elmassry Mohamed Donia ID microbiome-encoded biosynthetic gene clusters that are enriched in Crohn’s disease patients & the small molecules they produce, which exacerbate disease when introduced to mouse models of colitis cell.com/cell-host-micr…



The loss of TBK1, or both TBK1 and the related kinase IKKε, results in uncontrolled cell death–driven inflammation. We show that TBK1/IKKε prevent premature cell death by limiting the activity of multiple death pathways in myeloid cells.FabianFischer science.org/doi/10.1126/sc…

Please RT! Looking for PIs working in microbiome, metabolism, cancer, allergies, autoimmunity, neurological and infectious diseases. We offer SPF-, gnotobiotic- and wildling-models + top notch equip., e.g. SONY ID7000, 10X Xenium, MACSima. Contact: [email protected]

Please RT, our latest work just published Nature Communications „ONE MICROBIOTA TO RULE THEM ALL“ doi.org/10.1038/s41467… A big THANK YOU to the entire team of great scientists! #wildlings doi.org/10.1126/scienc… FAU Erlangen-Nbg Joachim Hornegger #HTA



New paper! Combining epidemiology and experiments uncovers surprising drug-host-microbiome-pathogen interactions. Congrats Aman Kumar Robyn Tamblyn and the rest of the team. nature.com/articles/s4158…


Please retweet! We hire PIs working in microbiome+metabolism+cancer+allergies+autoimmunity+neurological+infectious diseases. We offer SPF-, gnotobiotic- and wildling-models + top notch lab and equip. (e.g. SONY ID7000/10X Xenium/MACSima). Contact: [email protected]