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Oxygen effectively ⬇ right ventricular afterload in an animal model of acute pulmonary embolism🫀🫁🐷 in this study by Mads Dam Lyhne et al. published in Critical Care Medicine journals.lww.com/ccmjournal/Abs… #translationalresearch #cardiology #PE The PERT Consortium® Aarhus Uni.hospital

Acute #PE ⬆️RV afterload and ⬇️RV function. Inodilators could theoretically flip those arrows. Soon to appear in Pulmonary Circulation. The Pulmonary Vascular Research Institute Asger Andersen Jacob Schultz Simone Juel Dragsbæk The PERT Consortium®

Congratulations to professor Jens Erik Nielsen-Kudsk who received the Dansk Cardiologisk Selskab (DCS) research award for his outstanding contribution to cardiovascular science 🏆 You are a huge inspiration to all of us 🎉🍾

You do preclinical #cardiovascular or #cardiac research? Regardless your scope and focus, you should consider #PV loops. See how in JoVE jove.com/video/62661 Jacob Schultz Christian Mortensen Anders Kramer Simone Juel Dragsbæk Asger Andersen Jens Erik Nielsen-Kudsk

Acute #PE ⬆️ RV afterload and ⬇️RV function. Ino-dilators may oppose both but few data exist. We investigated three ino-dilators in PE with beneficial hemodynamic profiles: doi.org/10.1177/204589… Pulmonary Circulation The Pulmonary Vascular Research Institute The PERT Consortium® Asger Andersen Jacob Schultz Simone Juel Dragsbæk

New directions in pulmonary vascular interventions discussed by Asger Andersen at #ESCCongress 🫁🫀#PE #CardioTwitter Jens Erik Nielsen-Kudsk Jacob Schultz Mads Dam Lyhne Anders Kramer Simone Juel Dragsbæk Julie Axelsen

Mads Dam Lyhne et al: Oxygen Therapy Lowers Right Ventricular Afterload in Experimental Acute Pulmonary Embolism Link: ow.ly/dA4s50G2rsE #CritCareMed SCCM Simone Juel Dragsbæk Christian Mortensen Asger Andersen Fig: O2 effects on RV function

Spoiler alert. Filming with JoVE today in the animal lab. Video on biventricular #PVloops in large animal model will soon appear pubmed.ncbi.nlm.nih.gov/34096927/ Anders Kramer Christian Mortensen Jacob Valentin Hansen Jens Erik Nielsen-Kudsk Jacob Schultz Simone Juel Dragsbæk Asger Andersen

Massive #PE completely obstructing the main pulm artery -> cardiac arrest. 💔 “luckily” it was just in our realistic closed-chest porcine model 💪💉🐖 See more: pubmed.ncbi.nlm.nih.gov/32436719/ and pubmed.ncbi.nlm.nih.gov/33870917/ The PERT Consortium® Jacob Valentin Hansen Jacob Schultz Simone Juel Dragsbæk

In animal models 🐖🐑🐁 of cardiovascular diseases ❤️🩸, biventricular #PV loops provide thorough investigation but consider closed chest approach for near-normal physiology. See our approach: pubmed.ncbi.nlm.nih.gov/34096927/ JoVE #PE #hemodynamics #research

Thank you Danish Cardiovascular Academy for an amazing #dcasummermeeting23 ☀️ We already look forward to next year’s meeting 🫀

Excited to share our work on developing a porcine model of #ChronicThromboembolicPulmonaryDisease 🐖🫁🫀 Mads Dam Lyhne Jacob Valentin Hansen Lina Karout Jens Erik Nielsen-Kudsk Asger Andersen Department of Cardiology Research AUH Aarhus University authors.elsevier.com/a/1hppdBEfCrHO9

🫀 New publication in Thrombosis Research by Simone Juel Dragsbæk et al. A porcine model of #ChronicThromboembolicPulmonaryDisease was developed🐖🫁 Autologous emboli was used, and showed resemblance to human #CTEPH in chronic clot formation 🩸🔬 link: sciencedirect.com/science/articl…