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Honored to receive American Gastroenterological Association (AGA) Fellowship-to-Faculty Transition Award to study perianal fistulizing Crohn's disease! @WUGastro @IbdWustl

AGA President John Carethers celebrating AGA Foundation awardees. Thankyou ⁦American Gastroenterological Association (AGA)⁩ for investing in the future of GI. Recognize anyone on the photo? ⁦@WUGastro⁩

Honored to receive Crohn's & Colitis Foundation Career Development Award to study cellular stress pathway in innate lymphoid cells in IBD! The Colonna Lab

We were disappointed to learn that a runner was not allowed to participate in this year’s New York City Marathon because of the accommodations needed for her ostomy bag. See our CEO Michael Osso's letter to the editor of the @NYPost here: bit.ly/3uaVUNs

Truly honored to receive the Lloyd Mayer Career Development Award #CCCongress2024, to study cellular stress response in innate lymphoid cells in IBD. @WUGastro WashU Medicine Division of Physician-Scientists The Colonna Lab Crohn's & Colitis Foundation

Honored to receive funding support from CTRFP to identify response biomarkers for anti-IL23 therapies in IBD Parakkal Deepak MD, MS, FACG @WUGastro Crohn's & Colitis Foundation

Excited to attend my first #DDW in Washington D.C. to present our recent studies in IBD! 35: Multiomics of perianal Crohn's disease. 38: Single-cell analysis of Crohn's-like disease of the pouch. 413: IRE1a-XBP1 controls ILC2 in intestinal inflammation and fibrosis. 529: ILC3

Have you marked your calendar for the WU Physician-Scientist Symposium? Friday, June 7, 2024.

The IRE1α/XBP1 pathway shapes ILC3 functions during intestinal inflammation Comment: Giuseppe Sciume Journal of Clinical Investigation jci.org/articles/view/… Paper The Colonna Lab Siyan Cao "Stewart", MD PhD jci.org/articles/view/…

We're pleased to announce that we've updated our social media handles to reflect our new branding. Follow us at WashU Medicine Inflammatory Bowel Disease Center and use the hashtag #WashUMedIBD to stay up-to-date on the latest news, research, and advancements from the WashU Medicine Inflammatory Bowel Disease Ctr

Open access link of our CD-like phenotype of IPAA, single-cell analyses vs pouchitis, all corrections done: Mucosal Single-Cell Profiling of Crohn’s-Like Disease of the Pouch Reveals Unique Pathogenesis and Therapeutic Targets Gastroenterology Siyan Cao "Stewart", MD PhD gastrojournal.org/article/S0016-…

Single-Cell and Spatial Multi-omics Reveal Interferon Signaling in the Pathogenesis of Perianal Fistulizing Crohn's Disease biorxiv.org/cgi/content/sh… #biorxiv_sysbio

Excited to see if ER stress-reducing agents (e.g., tauroursodeoxycholic acid, or TUDCA) may become a new therapeutic option for CD of pouch! Matthew Ciorba MD Parakkal Deepak MD, MS, FACG WashU Medicine Division of Gastroenterology WashU Medicine Inflammatory Bowel Disease Center

Loss of ATG7 in microglia impairs UPR, triggers ferroptosis, and weakens amyloid pathology control rupress.org/jem/article-ab…, in this work we linked autophagy with UPR and ferroptosis in the microglial response to AD Zhangying Cai The Colonna Lab 🥳🍻🆗

Parakkal Deepak MD, MS, FACG Y-ECCO 3/4 🎤 Siyan Cao "Stewart", MD PhD is set to present cutting-edge work at #ECCO2025! 🧬 DOP127 (Feb 21, 17:45) – A novel epithelial junction gene in early-onset IBD 🧪 DOP095 (Feb 21) – IL-23-activated cells as biomarkers for RISA response 🦠 DOP117 – Innate lymphoid cells in colitis & fibrosis

Read the ICTS Digest! Get to know the 2025-2026 CTRFP Awardees, register for the 7th ICTS Symposium, read articles in Missouri Medicine online journal & more! @WashUMedicine WashU Medicine Department of Medicine WashU Medicine Department of Surgery WashUMedMIR Mizzou Nursing Saint Louis University Read more> l8r.it/03EM

Hosting Edward Loftus #LouisCohen in-person for our WashU Medicine Inflammatory Bowel Disease Center inaugural research symposium today 3/7 followed by Laurent Peyrin-Biroulet virtually for #IBDCME tomorrow. 👀 forward to an excellent day of research presentations Siyan Cao "Stewart", MD PhD @GwenRandolph_ #Ta-ChiangLiu & many trainees

Honored to receive the generous support from ACG to study type 2 immunity in patients with eosinophilic esophagitis WashU Medicine Division of Gastroenterology

Congratulations Siyan Cao "Stewart", MD PhD MD, PhD WashU Medicine Division of Gastroenterology on receiving the 2025 @AMCollegeGastro Clinical Research Award. This award supports research intended to improve the management of eosinophilic esophagitis (EoE), a chronic inflammatory disease. More> l8r.it/3B6o