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New research from @lefo1984 & Brigham and Women's Hospital Dana-Farber colleagues reports #Parkinsons-associated mutations in the α-Synuclein gene affect the biochemistry, architecture, & function of synapses; Hypothetical model proposed cell.com/cell-reports/f…

Altered conformation of α-synuclein drives dysfunction of synaptic vesicles in a synaptosomal model of Parkinson’s disease dlvr.it/S3DymP

Really excited to share our new strategy combining deep learning predictions, epigenetic profiling, genetic perturbation to dissect gene regulatory elements at base resolution, and find transcriptional fulcrum in regulating immune response~ biorxiv.org/content/10.110…