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Virus snowflake decorations are falling on our lab Christmas tree! 🦠 ❄️ Meanwhile real snowflakes fall outside 😃 🎄 thanks for the inspiration Hutchinson Lab MRC-Uni of Glasgow Centre for Virus Research and for activating everyone Sonja Fernbach

#Aerosol acidification important for inactivation of #airborne #Influenza & #SARSCoV2. Unintentional removal of acids & elevated NH3 levels indoors may prolong virus persistence. Overlooked role of #pH important for #virus transmission & mitigation. pubs.acs.org/doi/10.1021/ac…

Congratulations to our own Irene A. Abela, Chloé Pasin & Magdalena Schwarzmueller who were awarded the #PfizerForschungspreis2023 for their work on how immunity to common coronaviruses may promote rapid development of SARS-CoV-2 immunity nature.com/articles/s4146… University of Zurich @usz Pfizer Inc.

#TGIFAPIA (Thank God It’s Friday and Paper Is Accepted)! Congrats Nicolas Fossat Emma Alberte Lundsgaard 👏🏻 Stay tuned for the SARS-CoV-2 miRNA interactome and its regulation of the host - pending the final sentence rephrasing as per reviewer request!

Slowly spreading Cologne carnival to all our neighboring countries 🥳 #KoelleAlaaf

Another piece in the puzzle of SARS-CoV-2 host interactions in place: Check out our comprehensive mapping of the viral and cellular miRNA interactome during infection! Congratulations Nicolas Fossat Emma Alberte Lundsgaard 👏🧬🧫🍾 #virus #mirna UCPH Healthscience

🇩🇰👩‍🔬🎙️👨‍🔬🇩🇰We are happy to announce 3 exciting talks for the next RNA society club in CPH! Join us for a fantastic and informative gathering, and spread the word to other RNA enthusiasts! 📅🏛️🍻🍿Date and location: 12 June 2023, 4 pm at Nielsine Nielsen Auditorium (Mærsk Tower).

Excited to share our labs first nature paper! In collaboration with VintherLab we show that hepatitis C virus #RNA is capped with FAD protecting it from innate immune sensing. rdcu.be/df8p5 Congrats Anna Sherwood and Lizandro Rivera-Rangel 👏🏻🍾 #HCV UCPH Healthscience

The in vivo #RNA binding proteome atlas is here! Meeli Mullari and Nicolas Fossat use our new #RBP #brain atlas to demonstrate deregulation of RBM5 splicing in #Huntington's disease. In Nature Communications with Nielsen Lab Agnete Kirkeby Niels Skotte CPRatUCPH rdcu.be/dhf0Y

In perhaps(?) more approachable terms, NPR reports on our novel finding that hepatitis C virus caps its genome to protect from immune recognition. Also out in nature rdcu.be/df8p5 and in print! npr.org/sections/goats… VintherLab #HCV #RNA University of Copenhagen Research UCPH Healthscience

Now online! SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9 dlvr.it/SwyK2d

Ordering the names in a paper's author list can be a surprisingly unpleasant process. A few years ago I decided to design an algorithm for determining author orderings, and it has worked well enough that I've used for everything within my purview since then. Here it is:

Honored and proud to receive an #ERCCoG European Research Council (ERC) 😀🧫🧬 This allows us to continue explore novel viral RNA capping mechanisms and protection from innate immunity. erc.europa.eu/news-events/ne… And yes, we are hiring - stay tuned! University of Copenhagen Research UCPH Healthscience Københavns Uni

We are hiring! Want to do a #Postdoc in #virus-host interactions and RNA biology? Join an ambitious, fun and intl environment in a great city? Are you a talented researcher with proven track record? Apply here 👇 jobportal.ku.dk/videnskabelige… Please RT. UCPH Healthscience University of Copenhagen Research

Curious about how hepatitis C related viruses can be used as models for immune responses and pathology? Check out our quick read Journal of Hepatology snapshot review on mice, rats, horses and monkeys! By Matthew Kennedy Sonja Fernbach #HCV #hepacivirus #animalmodel authors.elsevier.com/a/1i%7EFxcOnAQ…

As we age, ~2% of us develop self-directed antibodies to interferon- 1 (IFN-1), which leads to lifelong increased susceptibility to virus infections such as #SARSCoV2 rupress.org/jem/article/22… Journal of Experimental Medicine Ben Hale UZH Virology Sonja Fernbach

Happy to share that our study on the development of anti-IFN autoAbs is out now 🥳 a big thank you to everyone who contributed to this exciting new data.

By tracing development of anti-IFN-I autoantibodies in individuals over a 35 year period, Ben Hale et al suggest that loss of self-tolerance prior to immune-triggering poses a risk for lifelong autoantibody-mediated functional IFN-I deficiency. hubs.la/Q02H59Hq0

Loss of tolerance precedes triggering and lifelong persistence of pathogenic type I interferon autoantibodies, say Sonja Fernbach (Sonja Fernbach), Nina Mair, Benjamin Hale (Ben Hale) & colleagues UZH Medical Virology University of Zurich: hubs.la/Q02H5yj90 #Autoimmunity #Immunodeficiency

.Sonja Fernbach, Mair, Ben Hale UZH Medical Virology and colleagues dissect how rare anti-IFN-I autoantibodies develop and weaken defenses over time, making some individuals more susceptible to infections. hubs.la/Q02H58D10 #Autoimmunity #Immunodeficiency #InfectiousDisease