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The special issue of Cancer Research is now online for #AACRPan24. Here are some of the “cancer research landmarks” articles on #PancreaticCancer: (1) Cancer research landmarks on cancer associated fibroblasts (CAFs), by Giulia Biffi & colleagues aacrjournals.org/cancerres/arti… (2) Cancer

Stromal Aspects of the Microenvironment and Tumor Microenvironment: Giulia Biffi, Mara Sherman, David G. DeNardo, Paul Timpson, and Max Wattenberg addressed this topic in a plenary session at the AACR Special Conference on Advances in Pancreatic Cancer Research. #AACRpan24

So impressive hearing Bryant Lab UNC discuss autophagic flux and macropinocytosis in #PancreaticCancer during the KRAS Cell Biology session at #AACRPan24

Erica D. Pratt demonstrates the potential of liquid biopsies to get a molecular snapshot of what is currently happening in #PancreaticCancer progression. Bioengineering offers advanced tools to monitor PDAC development over time. #AACRPan24

Our dinner tradition of current & former members of the Maitra Lab continues at #AACRPan24. It was wonderful to catch up with everyone. Thank you AACR Let's Win Pancreatic Cancer 💜 for the two scholar in training awards. Exciting day of science for all of us in #PancreaticCancer research.

Checkout new paper from our lab in Nature Genetics link: nature.com/articles/s4158… We mapped pancreatic cancer ecosystems across primary tumors and metastases using spatial transcriptomics on matched samples . Ateeq M. Khaliq PhD Bassel El-Rayes, MD IU Simon Comprehensive Cancer Center

iStar predicts gene expression with near-single-cell resolution from histology images go.nature.com/47m0Mgk rdcu.be/dUtvJ

Online Now: Cross-tissue human fibroblast atlas reveals myofibroblast subtypes with distinct roles in immune modulation dlvr.it/TDTSGq

This is a nice summary of the mechanisms of action of various KRAS inhibitors from Adrienne Cox & Channing Der in their Science Magazine perspective.

Congratulations to Fredrik Thege for receiving the uber competitive Hirshberg Foundation Seed Grant for his #PancreaticCancer research. Dude’s on a roll. Find him at #BMES2024 👇🏽

Kathy DelGiorno Dr. Pat Soon-Shiong What changed in the US in the mid to late-70s? Factoring in approximately 5-10 years for cancer development, the inflection point for young onset colorectal cancers started in the mid-80s for both sexes. And has never looked back. TV dinners? Plastic bottles?

In summary, the atlas Nina has built has collated scRNA seq data from >700,000 cells. Link to paper below: aacrjournals.org/clincancerres/…

CRISPR-StAR enables high-resolution genetic screening in complex in vivo models go.nature.com/4giANvD

A really comprehensive fibroblast review in primary and metastatic cancers! In Trends in Cancer from Giulia Biffi Marta Zaccaria Priscilla Cheng Wonderful job! Illustrations below highlighting (A) Cues that contribute to fibroblast heterogeneity in cancer (B) Fibroblast Cancer cell

The first example of how the impressive scRNA seq data set in #PancreaticCancer (collated by Dr. Nina Steele) can be leveraged for hypothesis generation & testing is now published in Clinical Cancer Research. Sita Kugel Fred Hutch Cancer Center demonstrates that HMGA2 is a reliable marker of the basal subtype

Very happy to share our article about AI agents in cancer research and oncology, with Yongju Lee Dyke Ferber & Aviv Regev, out in Nature Cancer now -> nature.com/articles/s4301… katherlab Nationales Centrum für Tumorerkrankungen Dresden NCT Heidelberg

🤠 👉🏽 🗽 news: I will be joining NYU Langone Health on September 1, 2025 as Director of the GI Cancer Center & Associate Director of Translational Research at Perlmutter Cancer Center at NYU Langone Health. I am excited to start the next chapter of the Maitra Lab in NYC & build a strong GI cancer research program.

Traditional selfie, this time with the EPC-Europ Pancr Club President 😉at EPC 2025 in Düsseldorf 💥🥳🥂European Society of Pathology (ESP) Claudio Luchini

From Malmö to MD Anderson to Columbus — Fredrik Thege, PhD, is joining #OhioStateSurg this fall! His research on KRAS-targeted therapies and pancreatic cancer models is pushing boundaries in cancer science. Welcome, Dr. Thege! 🎉

Exciting news! This fall, I’ll be joining Ohio State Wexner Medical Center Surgery Dept. as an Assistant Professor 🎉🧬🔬 My lab will focus on modeling therapy response in pancreatic cancer and uncovering powerful combinatorial treatments. Can’t wait to get started! #PancreaticCancer The James The Ohio State University Wexner Medical Center