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I loved attending CSHL Meetings single cell analyses meeting last week and talking about our recent work developing SPARCS. Thanks to the organizers and all attendees for making it a memorable event #cshlsca

Great opportunity to find out more about SPARCS our genome-wide image-based CRISPR screening platform.

Protein interactions are the foundation of functional and healthy cells. We Matthias Mann Lab are proud that our work for mapping the cellular yeast #interactome on a global scale is now published nature. nature.com/articles/s4158… yeast-interactome.org #proteomics #massspectrometry

In London to attend Crick BioImage Analysis Symposium symposium. Looking forward to hearing what’s new in the world of image analysis and connecting with other participants.

Come find me at Crick BioImage Analysis Symposium poster #21 to discover SPARCS our recently developed platform for microscopy-based genetic screens at genome scale. In case you can't attend, you can also checkout our preprint: biorxiv.org/content/10.110… listen to our webinar: leica-microsystems.com/science-lab/li…

Stoked to see scPerturb finally out! We worked with Tessa Green and Stefan Peidli to make all datasets available in pertpy together with fast implementations of the distances and distance tests. See pertpy.readthedocs.io/en/latest/usag… and pertpy.readthedocs.io/en/latest/tuto… and pertpy.readthedocs.io/en/latest/tuto…

Was a pleasure to chat with the amazing team Myllia Biotechnology! Thanks for the invitation and the fantastic organisation. Happy to discuss image-based genetic screening at any time 🎇🧬🙏

Thrilled that our work on genome-wide genetic screens for image-based phenotypes was awarded the „Molecular Omics“ poster prize @ EMBO symposium „AI and biology“. Thanks to Royal Society of Chemistry for promoting our work with Sophia Mädler Matthias Mann Lab HornungLab Fabian Theis 🙏 #EESAIBio

Excited that SpatialData is out Nature Methods! With Oliver Stegle & Josh Moore labs, we introduce & implement a dataframework & fileformat for multimodal spatial omics, based on the openmicroscopy standard. Read at nature.com/articles/s4159… & try here spatialdata.scverse.org.

1/7 Matthias Mann Lab and Georg Wallmann Georg Wallmann are proud to announce alphaDIA, our open source, next generation DIA search engine. Check out the preprint bioRxiv biorxiv.org/content/10.110…

Loved presenting at #scverse24 today. So many interesting followup discussions already!

PhD ✅ Excited for what's up ahead 🚀 Many thanks to my colleagues, friends and family for all of the support throughout this journey🧸It wouldn't have been possible without you. Especially big shout-out to Matthias Mann Lab Niklas Schmacke Veit Hornung @BoehringerIngelheimFonds IMPRS-ML

Published today! Spatial proteomics reveals JAK/STAT as a target for Toxic Epidermal Necrolysis, an often fatal skin reaction to common medication. We validated our findings in pre-clinical models & successfully treated the first patients worldwide.🧵⬇️ nature.com/articles/s4158…

We just release alphaDIA 1.8.2 including some new step-by-step guides for #Proteomics. Learn how to: • Run DIA searches from the GUI • Create custom PTM models with DIA transfer learning • Evaluate model performance with detailed metrics alphadia.readthedocs.io/en/latest/guid… #TeamMasSpec

Excited to have contributed! Single-cell image representations generated using scPortrait and DL allowed us to identify molecular processes behind different aggregate morphologies in AADT #Alpha1Awareness Check out scPortrait for your own projects github.com/MannLabs/scPor… #scverse

📢 Postdoc opening! 📢 Sorek Lab and HornungLab are looking for outstanding candidates for a position at the intersection of computational biology & innate immunity. Dive into impactful research across two dynamic fields. Interested? Let’s connect! 👇 genzentrum.uni-muenchen.de/career/postdoc…

Excited to present my work on building single cell representations based on microscopy images at the upcoming #CBIAS2024 conference 😊 See you in London ✈️

🚨 Today's the day! #CBIAS2024 is kicking off this morning! buff.ly/4fITsAq #BioImageAnalysis

It was my pleasure presenting our work on scPortrait at #CBIAS2024 today! Here the relevant links from my talk: - scPortrait code base: github.com/MannLabs/scPor… - SPARCS platform : doi.org/10.1101/2023.0… - AADT paper: doi.org/10.1101/2024.1…

Excited to have contributed! Single-cell image representations generated using scPortrait and DL allowed us to identify molecular processes behind different aggregate morphologies in AADT #Alpha1Awareness Check out scPortrait for your own projects github.com/MannLabs/scPor… #scverse