
Sophie Helaine
@sophiehelaine
Microbiologist at Harvard Medical School - Helaine lab - Salmonella persisters
ID: 835242593927712768
http://helainelab.com 24-02-2017 21:38:47
61 Tweet
1,1K Followers
147 Following


Phages cooperate to tackle CRISPR-Cas3 and Cas9! Exciting paper out from (brave) first student to join the lab @AdairLBorges, with key contributions from fantastic undergrad (!) Jenny Zhang, @MCFRollins (Wiedenheft lab), and Beatriz A. Osuna 🇲🇽 #bigweek tinyurl.com/y9s2lbqz. 1/2

Latest from @Fillouxlab, Tse7 is the latest #antibacterial #T6SS #effector protein from #Pseudomonas and is a DNase, published in PNASNews Well done Panayiota Pissaridou Luke Allsopp Despoina Mavridou @CMBI_Imperial Article: imperial.ac.uk/news/189108/to… News article: pnas.org/content/early/…


I am co-organizing, with Sophie Helaine, an EMBO workshop on Toxin-Antitoxin Systems in Bacteria! Covering every aspect of TA systems - structure, function, and evolution. 15-17 April 2019 outside London. Lots of speaking slots for students and postdocs... meetings.embo.org/event/19-toxin…

Unlocking the secrets of #Salmonella persistence. New work from Sophie Helaine reveals that Salmonella persisters are metabolically active & can reprogram macrophages via SPI-2 effectors to dampen #immune responses Science Magazine science.sciencemag.org/content/362/64…


Here are links to the free full-text and PDF reprint of our recent Science Signaling paper on caspase-8, p62 and nutrient-sensing versus autophagy (scroll down to Research Highlights section for the links). Julia Sanchez Garrido Vanessa Sancho-Shimizu imperial.ac.uk/people/a.sheno…

New research by Imperial Department of Medicine & Helmholtz Institute Würzburg (HIRI) unravels how bacterial persister cells manipulate our immune cells, and may help explain why some people suffer from repeated bouts of an illness ow.ly/WGBe30mTNsp



CMBI NEWS Starting in January 2019, Julien Vaubourgeix will join the CMBI at Imperial College London to investigate the mechanisms by which Mycobacterium tuberculosis enters and exits persistence, a phenotypic state of tolerance to antimicrobials. Julien Vaubourgeix Welcome Julien




And the Van Leeuwenhoek Award goes to Daphne Stapels “Salmonella persisters undermine host immune defenses during antibiotic treatment” #ssm19


Scientists and other academics should follow this excellent example & refuse to speak on all male panels in conferences/scholarly meetings. This includes as keynote speakers or in round table discussions. A change in gender diversity has to happen quickly washingtonpost.com/health/nih-dir…

Woohoo! Helmholtz Institute Würzburg (HIRI)‘s Emmanuel Saliba and Universität Würzburg #UniWürzburg‘s @DolkenL just published in nature! They were able to visualise the battle between virus and host cells at the #SingleCell level. Have a look at: nature.com/articles/s4158…

Our scSLAM-seq paper is out in Nature nature! It is an amazing collaboration with Lars Doelken @DolkenL and Florian Erhard Universität Würzburg #UniWürzburg with the help of Fabian Theis Fabian Theis. Thousands thanks guys! nature.com/articles/s4158… #hiri #singlecell

Preliminary program for the 2020 GRC on Microbial Stress (which I'm co-organizing with Jade Wang 王珏) is live! Should be a great conference, as always, with lots of speaking slots selected from abstracts! And a GRS will precede the GRC. Register at: grc.org/microbial-stre…


