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Ni-Catalyzed C–H Alkylation of (hetero)arenes: Super simple, broad scope, enabled by sulfonylhydrazides! Appearing today in ChemRxiv (chemrxiv.org/engage/chemrxi…). An awesome joint venture with the amazing Engle Lab. Quick Summary: A new method for facile C–H alkylation of a

As a student, I was inspired to pursue a career in pharma by reading about the amazing synthetic chemistry innovations that were happening there. I hope this article can do the same for the next generation of pharmaceutical chemists. #MerckChemistry pubs.acs.org/doi/10.1021/ac…

Very happy to share that our last work: "Photocatalytic deoxygenative Z-selective olefination of aliphatic alcohols" has found home in Nature Communications!!! Many congrats to Sai Narayanan, Irene Sánchez Sordo, Carla Aira Rodríguez and Emanuele Azzi for the amazing work! rdcu.be/ef9VO

We made a few more limonoids.... chemrxiv.org/engage/chemrxi…

Synergistic LMCT and Ni Catalysis for Methylative Cross-Coupling Using tert-Butanol: Modulating Radical Pathways via Selective Bond Homolysis | Journal of the American Chemical Society Total Synthesis and Methodology Highlights pubs.acs.org/doi/10.1021/ja…

Appearing today in nature : nature.com/articles/s4158…

Congratulations to Ryan and Moto on the publication of their 1,2-acyl transposition in 2,3-dihdyrobenzofurans in Science! science.org/doi/10.1126/sc…

Excited to share our new paper with Qin Lab. Recently, Novartis filed SF5 containing drug candidate IWY357. SF5 has been an under appreciated FG with huge medchem potential and synthetic challenges. Here we made it easier☞ chemrxiv.org/engage/chemrxi… Congrats to the entire team

Do you want to uncover Nature's secrets for guaianolides? Check our latest publication! Many congrats Maria for the excellent work! Decoding Guaianolide Biosynthesis: Synthetic Insights into Pseudoguaianolides and Seco-Guaianolides pubs.acs.org/doi/10.1021/ac…

Concise Total Synthesis of Ambiguine P | Journal of the American Chemical Society Total Synthesis and Methodology Highlights pubs.acs.org/doi/10.1021/ja…

Our recent work in steroid synthesis, which features a tandem Negishi/Heck cross-coupling and a Baran reductive olefin coupling (BROC), is now out in J. Am. Chem. Soc.: pubs.acs.org/doi/10.1021/ja…

You’re going to love this mechanism! Louis Barriault reported a beautiful cationic reaction cascade to access highly functionalized bicyclo[m.n.1]alkanones. What is the mechanism of the reaction?

We’re excited for #CSC2025 next week! Come see what our group has been working on, featuring talks by Tim, Louis, and Tegan, and posters presented by Josh, Chad, Soufian, Lucas, and Tim. Chemical Institute of Canada

Congratulations to Martin Hébert and Gabriel Bellavance on their recent pub in J Org Chem/Org Lett! Check out this article showcasing our lab’s efforts and ultimate success in developing advanced synthetic strategies toward ginkgolide diterpenoids: pubs.acs.org/doi/10.1021/ac… uOttawa Science

Congratulations to Avery Morris and Tegan O'Brien on their recent publication in ChemEurJ: Chemistry - A European Journal! Check out their work on the photoredox-catalyzed hydroalkylation of C(sp3)-H acids here: …mistry-europe.onlinelibrary.wiley.com/doi/full/10.10… uOttawa Science

Enzymatic Stereoselective Nucleophilic Cyclization Governs Atypical Spirotetronate Assembly in Lucensimycin A Biosynthesis | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/ja…

Group pic 2025 📸

Structure and Mechanism of the Azomycin Biosynthetic Enzyme RohQ That Catalyzes a Spontaneous Cyclodehydration | Journal of the American Chemical Society University of British Columbia pubs.acs.org/doi/10.1021/ja…

Today in Science Magazine, we report a method to replace the C2 of pyridines with N, affording pyridazines. The change from electronically consonant (pyridine) to dissonant (pyridazine) opens retrosyntheses not typically available to the latter. science.org/doi/10.1126/sc…

Total Synthesis of Paxdaphnine A and Daphlongamine B via an Aza-Prins Cyclization Strategy | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/ja…