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Sixteen new Alzheimer's disease susceptibility genes discovered medicalxpress.com/news/2025-02-s…

Today we report the directed evolution of HUH (a sequence-sequence covalent protein tag for ssDNA labeling) into rHUH, a sequence-specific covalent protein tag for RNA labeling. rHUH was hard to engineer: the initial HUH template had no RNA activity, so we started with RNA-DNA

We’ve always wondered if PMI leads to changes in snRNAseq data (spoiler: it does). So, we did the study and decided to publish it for others to consider. Post-mortem interval leads to loss of disease-specific signatures in brain tissue eneuro.org/content/early/…

It’s almost BAW time🧠 Be part of this rewarding opportunity to teach Alachua county’s K-12 students about the brain through different interactive activities throughout the week of March 24th Check out our website for more information or follow the QR code to sign up to volunteer

NIH is centralizing peer review of all applications for grants, cooperative agreements and research and development contracts within the agency’s Previously the NIH Center for Scientific Review. This is expected to save NIH more than $65 million annually & make the review process more efficient.

…arneurodegeneration.biomedcentral.com/articles/10.11… Out now! Probe‑dependent Proximity Profiling (ProPPr) of Phospho‑Tau‑Associated Proteomes across Tauopathies by Dmytro Morderer 🇺🇦 and Melissa C. Wren, Ph.D. Great collaboration with Prof. Melissa E. Murray 📸🔬 and Dr. Dennis Dickson! Mayo Clinic Neuro Molecular Neurodegeneration CZI Science The National Institute on Aging (NIA)

MBI researcher Dr. Laura Ranum has been named a University of Florida distinguished professor, FLORIDA’s highest faculty honor. She will deliver a distinguished professor lecture at 2 p.m. Monday (3/31) in the MBI’s DeWeese Auditorium. Learn more: bit.ly/4hNiJKd

The ratio between levels of two synaptic proteins in cerebrospinal fluid predicts future cognitive resilience versus decline among presymptomatic & early #Alzheimer’sDisease individuals harboring amyloid and tau pathology. #biomarkers Hamilton Oh Tony Wyss-Coray nature.com/articles/s4159…

We continue to expand our collaborative studies with Craig Forest, looking at brain region/cell type vulnerabilities in the face of early Alzheimer's pathology- in this new preprint: biorxiv.org/content/10.110… Great job Mercedes, and thank you The National Institute on Aging (NIA) for supporting this work!

✨Introducing our new review series "Neuroimmune Dysregulation: Unveiling the Pathways to Neurodegeneration" led by Drs X. William Yang & Li Gan This series aims to consolidate the complex interplay between the immune system & neurodegenerative diseases! bit.ly/4cP9CrA

'Research models to study #LewyBodyDementia' Suelen Lucio Boschen, Aarushi A. Mukerjee, Ayman H. Faroqi, Ben E. Rabichow...John Fryer John Fryer, PhD Mayo Clinic Neuro #Parkinsons #synucleinopathy bit.ly/3EAS4Tf

In the latest episode of Cup O' Joe, Interim Provost Joe Glover visited MBI researchers Drs. Stefan Prokop and Matt LaVoie for a tour of the FLORIDA Neuromedicine Human Brain and Tissue Bank. youtube.com/watch?v=IdAgrZ…

Congrats to Gainesville High School's Navya Goyal for representing the MBI at the USA Brain Bee at Rutgers University on Saturday. After winning the Alachua County Brain Bee, she advanced to the national stage to compete w/ the country's top students in neuroscience knowledge.

With funding from the NIH, UF McKnight Brain Institute researcher, Dr. Carol Mathews, co-led the most extensive study to date into the genetics of OCD. news.ufl.edu/2025/05/resear…

Today, the FDA cleared for marketing the first in vitro diagnostic device that tests blood to aid in diagnosing Alzheimer’s disease. This is for the early detection of amyloid plaques associated with Alzheimer’s disease in adult patients, aged 55 years and older, exhibiting signs

New online! Synapse vulnerability and resilience across the clinical spectrum of dementias bit.ly/3SUHzNX

Inspired by her mother’s battle w/ Parkinson’s MBI researcher Dr. Vinata Vedam-Mai pursued a career in neuroscience & studies the immune system’s role in Parkinson’s. She also teaches Bharatanatyam, a classical Indian dance, to carry on her mother’s legacy youtube.com/watch?v=0y6suJ…

Gia Paterno and members of Dr. Giasson's lab recently developed and characterized a highly selective monoclonal antibody against tau phosphorylated at Thr217, a form of tau closely associated with Alzheimer's Disease. Read more about it here: nature.com/articles/s4159…

Is it your first time (or even your 10th time) giving a talk at a big conference like #AAIC25? Timing is important for your confidence, and out of respect for the audiovisual team, your co-chairs, and hybrid audience. 10-minute presentation tips: Sketch out 10 slides on paper

Highly reliable sources tell me NIH will still fund purely animal model grants (new ones too). NOAs (notice of awards) will be more human focused & justification for animal models must be made but $ for new & funded animal grants will continue. nature Science Magazine HHS.gov