print("Hello World")

doi.org/10.1021/acssyn…. Mohr and coworkers recently developed a CRISPR-Cas12a platform to stably integrate genes into several loci within T cells by NHEJ. Robust technologies like CAR T exist, but these cells have been fairly difficult to manipulate by CRISPR-Cas in the past.

nature.com/articles/s4158… Recently, Bridge and coworkers engineered a light-reactive anti-eGFR fragment that can now cross link upon activation with 365 nm light, using orthogonal tRNA/tRNA synthetase pairs to incorporate benzoyl-L-phenylalanine photocrosslinker.