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The #hypothalamus plays a large role in coordinating the array of neuronal signals that are responsible for keeping the body in a stable state. A special issue of Science unpacks this key brain region’s impact on physiological and behavioral homeostasis. scim.ag/4AG

Flavor-nutrient learning unveiled: AgRP neurons, key drivers of feeding behavior, play a surprising role. 🧠🍽️ #neuroscience 👩‍🔬👨‍🔬Monell Center Penn 🔗sciencedirect.com/science/articl…

Proud to share our latest work in Kidney International showing protective effects of #GLP-1 receptor agonists on the #kidney Outstanding collaboration with Daniel J Drucker Prof Sam El-Osta Prof Andrew Murphy Andrew Advani Dr Karly Sourris Monash University Baker Institute kidney-international.org/article/S0085-…

Online now in Neuron ! A tale of two neurotransmitters (glutamate and dopamine). We show how VTA glutamate projections to NAc paradoxically promote reward and aversion. What we found may surprise you! sciencedirect.com/science/articl…

GHSR plays a key role in inflammation, and macrophage GHSR promotes macrophage infiltration and induces pro-inflammatory polarization. Thus, GHSR may serve as a novel immunotherapeutic target for treating obesity and its associated comorbidity.doi.org/10.1016/j.molm…

Take home message: If U want big islets quickly, reduce your ghrelin levels. The culmination of a multi-yr project by postdoc turned Instructor Deepali Gupta Dr. Deepali Gupta and middle schooler turned high school graduate Avi Burstein. More to come from them. With help from John Campbell

An analysis of more than two million papers in life sciences shows a strong gender bias in citations: papers with female lead authors get fewer citations than do those led by male authors in subsequent male-led papers go.nature.com/3GYxSZ6

We’ve all heard of place cells: neurons that form a “cognitive map” representing the structure of the outside world. But what about our own structured behaviours? We took a deep mechanistic dive, out now on bioRxiv : biorxiv.org/content/10.110… 🧵below:

The #hypothalamus plays a large role in coordinating the array of neuronal signals that are responsible for keeping the body in a stable state. A recent issue of Science unpacks this key brain region’s impact on physiological and behavioral homeostasis. scim.ag/5lv

Back-to-back papers in Nature Metabolism today: a surprising connection between the appetite-suppressing metabolite Lac-Phe and metformin-associated weight loss. From Lydia Lynch and Shuke Xiao 肖舒克 Sarafan ChEM-H nature.com/articles/s4225… nature.com/articles/s4225…

Association between dietary sugar intake and depression in US adults: a cross-sectional study using data from the National Health and Nutrition Examination Survey 2011–2018 | BMC Psychiatry | Full Text bmcpsychiatry.biomedcentral.com/articles/10.11…

New insights into #appetite regulation: Research uncovers the role of the vagus nerve in mediating the effects of gut hormone PYY3-36 on food intake. Understanding this mechanism could pave the way for novel anti-#obesity treatments. 👩‍🔬🧑‍🔬Imperial College London 🔗sciencedirect.com/science/articl…

HNNA review for 2023 now published. The olfactory bulb: A neuroendocrine spotlight on feeding and metabolism - Stark - 2024 - Journal of Neuroendocrinology - Wiley Online Library onlinelibrary.wiley.com/doi/full/10.11…

GLP-1 medicines produce adverse events, predominantly gastrointestinal, transient in most. Yet controversy continues surrounding what AEs are rare but real vs. alleged but not rigorously proven in RCTs or real world data. Free to read Diabetes Care, a research journal of the ADA 🌟 diabetesjournals.org/care/article/d…

New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor dlvr.it/T8HJjw

Excited! My work has received over 1,000 views since publication! Read it here onlinelibrary.wiley.com/doi/10.1111/jn… #ViewsMilestone

Molecular connectomics identify local inputs to AgRP neurons and reveal a circuit through which GLP-1RAs suppress appetite in mice Nature Metabolism nature.com/articles/s4225…

New studies in mice revealing distinct roles for prolactin-related peptide and its receptors in control of food intake Molecular Metabolism Randy J. Seeley, Ph.D. University of Michigan sciencedirect.com/science/articl…

💕 Is lasting love more likely if you date only other scientists? 💕 How much should you talk about your research on a first date? Researchers lift the lid on their experiences of when science meets affairs of the heart go.nature.com/3YIC4p7