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Paroxetine‐mediated GRK-2 inhibition in STEMI: a greater reduction in late gadolinium enhancement in the experimental compared with the control group at 12  weeks did not translate into differences in echocardiographic or clinical outcomes at 1 year. ahajournals.org/doi/10.1161/JA…

Enterococcal colonization of the groin and isolation of enterococci in TAVR-associated IE --> a change in antimicrobial prophylaxis is warranted and should be changed to antimicrobial prophylaxis with a compound that is active against enterococci. authors.elsevier.com/c/1fnpXiVO07NV…

In an analysis of 1732 TAVI patients, ellipticity of the aortic annulus did not affect procedural and device outcomes irrespective of transcatheter heart valve design and generation. doi.org/10.1002/ccd.30… Daijiro Tomii Taishi Okuno Stefan Stortecky

AV annulus ellipticity & #TAVR outcomes 1732 pts prospective TAVR Bot registry #THV dislocation/embolization ⬆️ w elliptical compared w circular annulus No signif differences in 🫀technical success 🫀Device success 🫀Intended valve performance 🔗 onlinelibrary.wiley.com/doi/10.1002/cc…

ESC TV On the Road 🚍 at #ACC23 Watch Stephan Windecker as he shares the 3-year outcomes from the Evolut Low Risk Trial

NOW at #ACC2023 #FLAME high-risk #PE registry results 🔥Inari Medical FT pts w 1.9% in-hospital mortality 🔥Context arm consistent w hx data 29.5% in-hospital mortality 🔥Trial stopped early due 2 overwhelmingly meeting pre-defined PGs @ interim Unheard of. Practice changing

5-yr outcomes from #Swiss-TAVI registry on self-expanding vs balloon-expandable valves on small annuli (area < 430 mm2). Analysis from #JACCINT showed self-expanding valves with: ⬇️ mean gradient ⬆️ EOA ⬇️ PPM Similar mortality ⬆️ CVA vs balloon bit.ly/3ZYgxHi

Clinical Outcomes in High‐Gradient, Classical Low‐Flow, Low‐Gradient, and Paradoxical Low‐Flow, Low‐Gradient Aortic Stenosis After Transcatheter Aortic Valve Implantation. #AHAJournals @WagenerM1 Stefan Toggweiler Stefan Stortecky ahajrnls.org/3No8Zc5

ATTR amyloidosis is frequently coexisting in elderly patients scheduled for TAVR. Clinical presentation, hemodynamics and echocardiographic parameters may unveil ATTR CM in AS patients - early outcomes after TAVR were comparable. Stephan Dobner ahajournals.org/doi/10.1161/JA…

Amyloid Transthyretin Cardiomyopathy in Elderly Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Implantation. #AHAJournals Thomas Pilgrim Christoph Gräni Stefan Stortecky ahajrnls.org/45dK170

1/2 "Compared to age- and sex-matched population, TAVR patients exhibit higher risk of stroke for up to two years post TAVR" Delighted to share our work from the SwissTAVI registry Stefan Stortecky Taishi Okuno Thomas Pilgrim SwissTAVI JACC Journals doi.org/10.1016/j.jcin…

Delighted to share our latest SwissTAVI output VKA vs DOAC after TAVI In a nutshell: VKA = ⬆️Mortality ⬇️stroke while ↔️bleeding Very nicely summarised in the🧵 below by Umair Khalid 🙏🏻 Stefan Stortecky Thomas Pilgrim Insel Gruppe JACC Journals jacc.org/doi/10.1016/j.…

The Special Trial: USAT Versus Surgical Pulmonary Embolectomy for Acute Pulmonary Embolism: USAT was not non-inferior in reducing RV/LV ratio. Indeed, surgery resulted in greater improvement of RV overload and reduction of clot burden EJCTS_ICVTS academic.oup.com/ejcts/article-…

#SimPub #CircTCT24 PEERLESS Randomized Control Trial: in patients with acute intermediate-risk pulmonary embolism (PE), large-bore mechanical thrombectomy (LBMT) significantly reduced adverse outcomes, comparted with catheter-directed thrombolysis (CDT) ahajrnls.org/3UuyGvP

Explore PE Management with Prof Felix Mahfoud, Prof Ingo Ahrens, Dr Stefan Stortecky & Dr Thomas Cuisset! 📚 ow.ly/tMxr50U36wh This one-hour programme highlights the latest guidelines, risk stratification and the highly anticipated data from the #PEERLESS study. Attend

Echo screening of TB patients facilitates early detection of CV involvement. Routine echo at baseline in all newly diagnosed TB patients may allow for timely medical management and prevent complications such as constriction and heart failure. JACC Journals sciencedirect.com/science/articl…

Find out how the PEERLESS RCT is transforming clinical data analysis with its innovative win ratio approach. In this 12-minute video with Prof Stefan Stortecky you will learn about: ✅ Study goals & design ✅ Key findings ✅ Impact on PE treatment decisions ✅ Future of

In the Bern TAVI registry, hemodynamic valve deterioration occurred in up to 1 in 4 patients throughout 10 years post-TAVI and was associated with a 5-fold increased risk of aortic valve reintervention. #JACCINT authors.elsevier.com/sd/article/S19… Bashir Alaour Fabien Praz Stefan Stortecky

New publication: “THE INDIVIDUAL FIBRINOLYTIC CAPACITY PREDICTS EFFICACY OF ULTRASOUND-ASSISTED CATHETER-DIRECTED THROMBOLYSIS IN PATIENTS WITH ACUTE PULMONARY EMBOLISM”. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/39884395/ Stefan Stortecky #BernCVRC

PEERLESS is a prospective multicenter RCT that compared mechanical thrombectomy with catheter-directed lysis for intermediate-risk pulmonary emboli. Drs. Zarina Sharalaya and Ripal Gandhi break down the study design and results, highlighting the most important takeaways. Full