
Lingyan Shi
@stimulatedraman
Associate Professor of Bioengineering at UCSD. We develop and apply optical nanoscopy to visualize metabolic dynamics in situ for studying aging & diseases.
ID: 91815368
https://www.jacobsschool.ucsd.edu/faculty/faculty_bios/index.sfe?fmp_recid=487 22-11-2009 16:07:29
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Single-color 3D MINFLUX of periodic paralemmin-1 (Palm1) along the axon of a mature neuron. YFP-Palm1 was detected with a nanobody against YFP in combination with DNA-PAINT. Image courtesy: Victor Macarron, MPI for Medical Research, Heidelberg, Germany More in the paper with


In this month's Technology Feature, Caroline Seydel explores how researchers are using label-free microscopy techniques to study complex biological systems, from living creatures to peptides. nature.com/articles/s4159…


Great catching up with our UC San Diego Bioengineering seminar speaker, Professor Darrell Irvine, and our colleagues from UCSD Engineering. Thanks for the photo idea Professor Lingyan Shi 🙏!


Check out our new paper in Nature Biotechnology sharing our latest kinase activity reporters! Led by former postdoc Michelle Frei, these reporters are based on HaloTag rather than an FP, for far-red imaging and superresolution! nature.com/articles/s4158…

🚨Preprint alert!🚨 Why do high-altitude populations have lower rates of metabolic syndrome and lower blood glucose? Superstar postdoc Yolanda tackled this❓tinyurl.com/2x7ptyn8 Gladstone Institutes Arc Institute UC San Francisco #hypoxia #oxygen


🏆 Science deserves to be celebrated. A recent story by Ian Sample in The Guardian details the fascinating life of David R. Liu, a professor at the Broad Institute of MIT & Harvard and one of the winners of the $3m Breakthrough Prize for Life Sciences, known as the “Oscars of







We are looking for talented postdocs/visiting students to join our team MIT Dept of BE and Koch Institute at MIT to innovate spatial multi-omics technologies, map clinical samples, and integrate AI/ML models to advance next-generation cancer immunotherapy. Please help to spread!!




