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In a collaboration between Buchwald Group & PenteluteLab, we developed peptide-encoded libraries (PELs) as a new platform for small molecule drug discovery. This work with @NathalieGrob is now out in Science Magazine science.org/doi/10.1126/sc… #ScienceResearch MIT Chemistry

Congrats to my colleague and age of empires teammate on this amazing piece of work. Be sure to check it out!

Now published J. Am. Chem. Soc. -- We designed new ligands that enable Cu-catalyzed room temperature C-N coupling reactions between aryl bromides and alkyl amines. Contributions from many members of the Buchwald Group group. pubs.acs.org/doi/10.1021/ja…

Room-Temperature Cu-Catalyzed Amination of Aryl Bromides Enabled by DFT-Guided Ligand Design Massachusetts Institute of Technology (MIT) @MITChemistry Buchwald Group Total Synthesis and Methodology Highlights #RT #CuCatalyzed #Amination #ArylBromides #DFTGuided #Ligand #Design pubs.acs.org/doi/10.1021/ja…

Excited to see all of the fantastic chemistry coming out of the Dong Group at Colorado State! Congrats Yuyang!

We are HIRING! We are looking for postdocs with expertise in synthetic chemistry to join our team at CSU. Come help us push forward the boundary in transition metal catalysis! Please see the following page for instructions: dong-organometallics.com/team #chempostdoc Chemjobber

#ProcterPOW: Buchwald Group disclose a new💎in Cu-catalysis. DFT-guided designer anionic ligands derived from diamines enable Ullman coupling to proceed at rt with wide substrate scope. 🧪 pubs.acs.org/doi/full/10.10…

Stereoselective Synthesis of Trisubstituted Alkenes via Copper Hydride-Catalyzed Alkyne Hydroalkylation | JACS University of Pittsburgh Peng Liu Group Massachusetts Institute of Technology (MIT) MIT Science Buchwald Group MIT Chemistry Total Synthesis and Methodology Highlights #Stereoselective #Alkenes #CuH #Alkyne #Hydroalkylation pubs.acs.org/doi/10.1021/ja…

Congrats to our team featuring Lun Hsin Kuo Mike Strauss James Law Dennis Kutateladze Simon Rössler Hsuan-Min Hung for coming in second place in this years MIT Chemistry volleyball tournament and big shoutout to everybody else who joined games throughout the tournament!

Great lecture by Steve Buchwald Buchwald Group! Inspiring stories of the history of Pd-catalyzed aminations and current progress on protein functionalizations.

The lab had a great time at the Boston Symposium on Organic and Bioorganic Chemistry yesterday, thank you to the organizers for a wonderful event. Mike Strauss gave a talk on copper-catalyzed cross-coupling and Simon Rössler presented a poster on peptide-encoded libraries.

#IKCOC-15 Three distinguished plenary speakers will illuminate the stage with their remarkable insights into chemistry. Join us in welcoming Prof. Buchwald (Buchwald Group) in Session 1, Prof. Meijer in Session 2, and Prof. Sodeoka in Session 3.

Steve in Kyoto! Had a great time at the Buchwald Group's Japanese reunion last night!

I became a conference photographer for amazing chemists Minakata-Lab. and Buchwald Group IKCOC-15→16

Along with Megan Greaves, seoungtae kim, and our friends at Bristol Myers Squibb, we developed a Cu-catalyzed C–O coupling protocol using our newly developed ligand family that features a new ligand, mild reaction conditions, and interesting mechanistic insights. onlinelibrary.wiley.com/doi/10.1002/an…

Had an amazing time at the Welch conference! Congratulations to Prof. Eric Jacobsen on receiving the 2024 Robert A. Welch Award in chemistry! The Welch Foundation Shoutout Grandpa Buchwald Buchwald Group #buchwaldbowtie