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This week Lucy Chappell visited Bangalore Medical College to meet research teams working on two pioneering NIHR Global Health Research projects in maternal and newborn health. Read more: ac.pulse.ly/d2rgjehgd6

(1) Cooling ineffective in LMIC, irrespective of birth depression severity/acidosis (2) 35% adverse outcomes even after short birth depression – WHY? thelancet.com/pdfs/journals/… Centre for Paediatrics & Child Health Andrew H Shennan OBE Lucy Chappell NIHR Global Health Atul Malhotra Gates Foundation

CRADLE VSA cited in this Economist article as an innovation that has contributed to this remarkable reduction in maternal mortality in Sierra Leone. ⁦NIHR Global Health⁩ ⁦Welbodi Partnership⁩ eur03.safelinks.protection.outlook.com/?url=https%3A%…

“Seven lessons to Share” Prof Lucy Chappell (Chief Scientific Advisor, Dept of health, UK): Do watch this, especially, if you are an early career researcher-It could change your life Gates Foundation Centre for Paediatrics & Child Health Atul Malhotra Professor Azeem Majeed NIHR Global Health youtube.com/watch?v=A_RUJv…

New IPD meta-analysis investigating the impact of cord strategies on preterm mortality published in The Lancet by Anna Lene Seidler (she/her) #neotwitter #EBNEOAlerts buff.ly/46lboM3

One of the best global health research teams doing world class qualitative research - Great opportunity

Gene expression shed lights into the high occurrence of HIE in South Asia and lack of hypothermic neuroprotection. jamanetwork.com/journals/jaman… imperial.ac.uk/news/251133/bl… Atul Malhotra Centre for Paediatrics & Child Health NIHR Global Health Andrew H Shennan OBE NeonatalUpdate Evidence-Based Neo Aubrey Cunnington MARCH Centre, LSHTM Professor Azeem Majeed

Levetiracetam not controlling electrographic seizures but are we giving it too late? sciencedirect.com/science/articl… Centre for Paediatrics & Child Health Atul Malhotra NeonatalUpdate Evidence-Based Neo Young Epilepsy International League Against Epilepsy ILAE BRITISH BRANCH CPN | Imperial College London

Super proud of my "Early Neurodevelopment Clinic" team. We were early adopters of international guidelines: pubmed.ncbi.nlm.nih.gov/28715518/ Read about sensitivity & accuracy of early assessments in new 📃 by Abdul Razak in JAMA Network Open: jamanetwork.com/journals/jaman… Evidence-Based Neo European Society for Paediatric Research (ESPR)

COMET pilot trial out (JAMA N) – highest [NAA] level in normothermia, followed by 48 h and lowest with 72 h cooling. Suggest caution on cooling babies with mild HIE outside a clinical trial Atul Malhotra Imperial Department of Brain Sciences Centre for Paediatrics & Child Health Hope for HIE ☀️ @peeps-HIE jamanetwork.com/journals/jaman…

Erythropoietin monotherapy given within 6h for 9 days, halved neonatal death in this multicentre pilot RCT from South Asia. Timing looks key to neuroprotection in HIE? fn.bmj.com/content/fetaln… Atul Malhotra @peeps-HIE Hope for HIE ☀️ Centre for Paediatrics & Child Health Ela Chakkarapani Andrew H Shennan OBE

Congrats to Constance Burgod on an outstanding PhD on gene expression in HIE. Finally, there is scope for HIE disease stratification. Start of an illustrious academic career (No head-hunters please)Centre for Paediatrics & Child Health @peeps-HIE Hope for HIE ☀️ Imperial Department of Brain Sciences Imperial Department of Infectious Disease

National Neonatology Forum (India) should be commended for their thoughtful position statement for de-implementation of cooling in LMIC – "primum non nocere" authors.elsevier.com/a/1j7qeLjtOl9lC NNFIndia @peeps-HIE Hope for HIE ☀️ Centre for Paediatrics & Child Health Atul Malhotra @Dr_KS_Gautham Newborn Brain Society

One more Super PhD without any corrections – Congrats to Dr Stuti Pant PhD. Imperial Department of Brain Sciences Centre for Paediatrics & Child Health @peeps-HIE Hope for HIE ☀️ Atul Malhotra Andrew H Shennan OBE Bliss Baby Charity

Is Quantitative research from Mars and Qualitative from Venus? We need to both to make sense of the data and to improve health outcomes – and that is all what matters ! Imperial Medicine Imperial Department of Brain Sciences Centre for Paediatrics & Child Health @peeps-HIE Hope for HIE ☀️ The Neonatal Society Andrew H Shennan OBE Tina Lavender

Congratulations to Dr Pallavi Muraleedharan on successful PhD defence on systemic factors and a prediction tool for HIE using AI @peeps-HIE Hope for HIE ☀️ Atul Malhotra Imperial Department of Brain Sciences Centre for Paediatrics & Child Health Andrew H Shennan OBE Tina Lavender

Fantastic opportunity to learn & engage with health professionals in Hisar, Haryana, India this week running ONE-Sim Education workshops to improve obstetric & newborn emergency management. #IPE #SimEd #MedEd Courtesy Dr Reema Garegrat Sudhin Thayyil CPN | Imperial College London Centre for Paediatrics & Child Health

Congratulations to Dr. Vaisakh Krishnan on successfully defending his PhD Viva! 🎉 His in-depth research on the timing and origin of brain injury in HIE in LMIC is truly outstanding. Imperial Department of Brain Sciences @peeps-HIE Hope for HIE ☀️ Centre for Paediatrics & Child Health

Best COMET site initiation ever! Huge thanks to Mel and the team at Plymouth – even the foundation officers got trained on expanded modified Sarnat staging. Excited to open COMET at Derriford Hospital soon! Newborn Brain Society @peeps-HIE Hope for HIE ☀️ Centre for Paediatrics & Child Health Atul Malhotra