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High Amount of Transcription Factor IRF8 Engages AP1-IRF Composite Elements in Enhancers to Direct Type 1 Conventional Dendritic Cell Identity cell.com/immunity/fullt…

Haha, that's me 😂😂😂

Sunkyung (Sunny) Kim Sunny Kim from the Murphy Lab presenting her most recent work at #MyeloidCells Keystone Symposia!

Kim, Murphy et al. Test Account show that tumor-derived IL-6 blocks development of type 1 classical #DendriticCells by inducing C/EBPβ in the common DC progenitor, which supports Zeb2 expression in the −165 kb enhancer, thus preventing pre-cDC1 specification bit.ly/3D4yOcx

Transcription factor C/EBPα is required for the development of Ly6Chi monocytes but not Ly6Clo monocytes | PNAS pnas.org/doi/10.1073/pn…

A new paper came out!!! science.org/doi/10.1126/sc…