Superb talk by Suzan Kors about organelle “hugging” the regulation of peroxisome-ER interactions in mammalian cells! #clescon @CLESUniofExeter University of Exeter Doctoral College

It was a pleasure to be co-chair of the CLESCon 2021 committee - very proud of the team! Thanks to all the amazing speakers and inspiring posters for making today a success. It was great to hear about the huge range of research being done by our PGR community @CLESUniofExeter

My PhD work in preprint ⬇️ 'Regulating peroxisome-ER contacts via the ACBD5-VAPB tether by FFAT motif phosphorylation and GSK3β' biorxiv.org/content/10.110…

Excited to share my PhD research - now published in Journal of Cell Biology! We show that #peroxisome🟢-ER contacts are regulated by phosphorylation and that GSK3β can inhibit these contacts by directly acting on the ACBD5-VAPB tether 👇

A pioneering study has revealed how cellular compartments (organelles) are able to control how much they interact and cooperate. exeter.ac.uk/news/research/…

We have a "News and Views" from Suzan Kors, Joe Costello & Michael Schrader University of Exeter about their work showing membrane contact is regulated both positively and negatively by phosphorylation. journals.sagepub.com/doi/full/10.11… The PO4 group can enhance or prevent FFAT-VAP binding.

Our review on VAP proteins is out! With an overview of their many binding partners 🪢 how they are hijacked by pathogens 🦠 and the role of mutant VAPB in ALS8 🧠 including lots of ER-#MembraneContactSites Frontiers - Cell Biology Joe Costello frontiersin.org/article/10.338…

A pioneering study, led by Professor Michael Schrader from the University of Exeter has shed new light on how subcellular organelles divide & multiply. exeter.ac.uk/news/research/…

Honoured to receive the 'Peroxisome Research Award' at #OEPM2022 last week for best #peroxisome paper published in the past 2 years. I couldn't have wished for a better ending of my PhD > I just submitted my thesis! Paper: doi.org/10.1083/jcb.20… Schrader lab at OEPM in Aveiro:🙌

Wondering how all those membrane contact sites are regulated? In this review we summarize different mechanisms that can control organelle tethering e.g. Phos, Ub, ROS, dimerization, interactors ↔️ #MembraneContactSites #BioEssays Joe Costello onlinelibrary.wiley.com/doi/10.1002/bi…

Congratulations, Dr Suzan Kors from Exeter Biosciences. It was a pleasure to act as your examiner LSI Exeter. A well-deserved graduation after 4 years of hard work! And thanks to Marc Fransen travelling all the way from KU Leuven. Peroxisomes rock!

I did it! I succesfully defended my PhD thesis Exeter Biosciences @GW4BioMedDTP Thanks to everyone who was part of the journey! I had an amazing time.

Want to join us in lovely Exeter to work on membrane contact sites? 6 month post-doc position available: jobs.exeter.ac.uk/hrpr_webrecrui…

Struggling with your protein immunoprecipitations? This methods chapter includes all my tips and tricks based on the >100 IP experiments I did during my PhD. In #peroxisomes 🟢 #MiMB Schrader Lab link.springer.com/protocol/10.10…

Online now: Peroxisomes - Methods in Molecular Biology 2643. All the tools & tricks to study the world of Peroxisomes🟢, Edited by Prof. Michael Schrader University of Exeter Faculty of Health & Life Sci University of Exeter, visit link.springer.com/book/10.1007/9…

Excited to be part of this:

Preprint from my PhD work: For this I went out of my 'mammalian cell culture zone', we explored the peroxisome🟢-ER contact site proteins ACBD4/5 and VAP in fruit fly and a filamentous fungus. doi.org/10.1101/2024.0…

Opportunity to join the fantastic team of Schrader Lab 🔬🥼!

We looked at peroxisomal ACBD4/5 proteins across evolution + exploring them in Drosophila and Ustilago revealed new roles in PO-ER contacts, neuronal/hyphal PO positioning, PO degradation, ... Schrader Lab Exeter Biosciences @GW4BioMedDTP Now in BBA doi.org/10.1016/j.bbam…

In their Review, Suzan Kors and Anne-Lore Schlaitz Uni Heidelberg highlight the dynamic remodelling of the ER for mitosis and discuss how these changes support cell division. journals.biologists.com/jcs/article/13…