🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

This Christmas, 5years on from the publication of the ICH E9 Addendum on #Estimands Suzie Cro & I describe a fictitious, festive RCT conducted by Santa 🧑🏼‍🎄 to answer the question: does a reindeer’s pre-flight meal impact performance? #trials BMC link.springer.com/article/10.118…

🎄All I want for Christmas…is a precisely defined research question! This festive paper by ICTU’s Suzie Cro & Rachel Phillips uses Santa's reindeer to explain the importance of using #Estimands in clinical trials🦌🎅 trialsjournal.biomedcentral.com/articles/10.11…

All I want for Christmas…is a precisely defined research question Estimands and ICH E9(R1) explained using the vehicle of Santa, carrots, mince pies and reindeer.. trialsjournal.biomedcentral.com/articles/10.11…

Do mince pies or carrots improve reindeer performance?🥕🥧How can #estimands help to ensure #trials answers the question of interest -despite reindeer shenanigans 🦌? Estimands explained this #Christmas in trialsjournal.biomedcentral.com/articles/10.11…

All I want for Christmas…is a precisely defined research question Read here! trialsjournal.biomedcentral.com/articles/10.11… Suzie Cro Rachel Phillips #Trials #OpenAccess

New paper. Led by Leila we cover the evolution of phase 3 vaccine trial design & analysis. We provide insights into innovations such as adaptive designs, Bayesian methods, the estimand framework, machine learning methods & advances in safety analysis doi.org/10.1093/cei/ux…

Register here to attend the *2nd Contemporary Clinical Trials Methodology Meeting* -a fantastic line-up of speakers in store across 1 or 2 days, including statistical day 1 covering multi-arm multi-stage trials, platform trials & target trial emulation! imperial.ac.uk/events/185985/…

Feeling the holiday spirit faded this #BlueMonday? Brighten your day and understand the joy of #estimands in a trial led by Santa—because estimands aren’t just for Christmas! trialsjournal.biomedcentral.com/articles/10.11…

How can we implement reference-based multiple imputation to handle #MissingData in #ClinicalTrials for longitudinal binary outcomes? We explored 2 different approaches. Find out which performed best here: onlinelibrary.wiley.com/doi/10.1002/si…

📢New publication: How to implement Reference-based multiple imputation for longitudinal binary data, lead by Suzie Cro with Matteo Quartagno Ian White & James Carpenter onlinelibrary.wiley.com/doi/10.1002/si…

Registration for our next in-person Contemporary Clinical Trials course is OPEN! This is a bespoke programme for lead investigators who are looking to plan and conduct their own trials There are only 10 places, so register early! Details and registration: imperial.ac.uk/medicine/resea…

Only 1 week left to book our 2nd Contemporary Clinical Trials Methodology Meeting, 2-3 April, with the exciting agendas and speakers in store below! >2nd April - statistical >3rd April - trial operations, data systems and data management Register here: imperial.ac.uk/events/185985/…

New publication in Journal of Clinical Epidemiology led by Louise Marston using multiple imputation to target a hypothetical estimand in a pandemic restriction-free world for a trial in schizophrenia - demonstrating the potential impact of the pandemic on the trial results sciencedirect.com/science/articl…

The expressions of interest form is now open for anyone who wishes to apply to attend the 'Roadmap Workshop: A road trip for PPI with Trials Methodology Research'. Please click the following link to access it: forms.office.com/e/kx5w4MgHad

📢 New job alert. We're recruiting a Lecturer in Digital Health & Clinical Trials ImperialCTU. We're seeking an experienced methodologist looking for a new leadership & research role to help us grow our portfolio of digitally enabled trials. shorturl.at/IioXW Closing 5 May

In 2023 Trials invited submissions that related to the collection, analysis & reporting of adverse events in clinical trials. In this editorial Victoria Cornelius & I summarise the submissions & discuss implications on clinical trials & future research rdcu.be/elLFa

New Publication 🔊: Investigating the trustworthiness of randomized controlled trials in osteopathic research: a systematic review with meta-analysis by David Hohenschurz et al in Journal of Clinical Epidemiology jclinepi.com/article/S0895-…

Missed the 1st PPI for Statistician Community of Practice webinar on the organising teams PPI? including our Suzie Cro Rachel Phillips & Laura Gray, Jonny Broomfield, Beatriz Goulao, Kara-Louise Royle, check out the recording here: leicesterbrc.nihr.ac.uk/ppismart/ppi-s…

Interested in a new way to impute missing data in clinical trials targeting treatment policy estimands? New blog post introducing **Retrieved Dropout Reference-Based Centred Multiple Imputation** statsci.co.uk/post/a-new-way…

📢Job alert! We are looking for an ambitious senior trial statistician to join an exciting new partnership between Imperial College London & Imperial College Healthcare NHS Trust, the Fleming Initiative, which aims to tackle antimicrobial resistance (AMR). imperial.ac.uk/jobs/search-jo…