SWON Alliance (@swonalliance) 's Twitter Profile
SWON Alliance

@swonalliance

An MRC-funded UK hub of research activity investigating a key component of antimicrobial resistance – the Bacterial Cell Wall.

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calendar_today27-04-2016 15:32:17

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Amongst the antibiotics that are a mainstay of human healthcare penicillins and successive generations of β-lactams have been most used #AMR

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β-lactam resistance is due to enzymes that destroy the antibiotic, permeability changes in the outer membrane or altering the target itself

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β-lactams target the final stage of bacterial cell wall peptidoglycan (PG) biosynthesis. PG is polymerized by penicillin-binding-proteins