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Deep Dive Slides #ACC2024 on SMART Trial. William Suh, MD Philippe Pibarot Amr Abbas thomas modine David J. Cohen, MD, MSc Mamas A. Mamas Dipti Itchhaporia, M.D., MACC , FAHA, FESC Athena Poppas, MD FACC NL valve w/ high gradient is NOT “dysfunction”-may be high EF! BEV EchoGradient > but CathGrad < SEV! MGrad and PPM not predictive!!

Today 22 years ago, on 16 April 2002 : the first #TAVI! Innovation, energy, teamwork and perseverance - read more about the life and times of Alain Cribier, a French interventional cardiologist whose work has impacted the lives of patients worldwide ➡️pcronline.com/About-PCR/40-y…

A quick glance from Philippe Pibarot comparing SMART trial vs. OPERA TAVI! #CardioTwitter #TAVR TAVR Bot

One of true structural heart emergency procedure. Acute severe bioprosthetic AI with cardiogenic shock. Successful emergent TAV-in-TAV with Sapien in Evolut Pro. great results and resolution of shock immediately.#TAVRinTAVR TAVR Bot Cath Lab Digest Edwards Lifesciences OhioHealth

Precise placement to avoid coronary obstruction without leaflet overhang

#TAVR poll When consenting a patient for TAVR with possible bailout open heart surgery, is the patient signing 1 consent that includes bailout or 2 separate consent forms, 1 for TAVR and 1 for possible open heart?

EuroIntervention Interesting bench study showing optimal result with pre and post dilatation of TAV in TAV. For those performing ViV TAVR in surgical valves, are you performing valve fracture pre, post, or both? #TAVR #TAVI

With regard to coronary revascularization pre #TAVR what is your *usual* approach until now? Pls vote & RT! #CardioTwitter

#TBT #TAVR #CardioTwitter Original Edwards TAVR SAPIEN valve 22F sheath, femoral cut down General anesthesia, Swan, TEE #TAVREvolution

#TBT #TAVR #CardioTwitter Second generation Edwards TAVR SAPIEN XT 18F sheath, double Perclose Still doing general anesthesia, Swan, TEE Didn't go to conscious sedation TAVR until SAPIEN3 #TAVREvolution

#TAVR 1 yr safety outcomes from ACURATE IDE Trial RCT - Acurate vs Evolut vs SAPIEN S3 had lower CV death, disabling stroke and PVL compared to other 2 devices. For years, we have been asking for comparative data from TVT registry. Where is the transparency? Time to open it up!

For those that do mitral TEER, which device do you prefer and why? #CardioTwitter #Structural #MitralRegurgitation #TMVR

Exactly 20 years ago, the 1st TAVR in the US was done by Dr William O’Neill at William Beaumont Hospital! Dr. Alain Cribier was the proctor. I was an interventional fellow watching from the control room. Those 5 seconds when I saw the valve being deployed, literally changed my

Death is an undeniable hard outcome. #TAVR trials suggest that outcomes between BEV and SEV are similar. But look at MAUDE database. Search 7/1/24 - 12/31/24, outcome death. Edwards SAPIEN = 22 records Medtronic Evolut = 228 records 10-fold higher with Evolut 😳 Why?

David J. Cohen, MD, MSc What would it take for TVT registry to be opened? Both Edwards TAVR and Medtronic Structural Heart would have to agree? American College of Cardiology The Society of Thoracic Surgeons

#TAVR poll Where is the cardiac surgeon during TAVR?

Is transcarotid TAVR a suitable alternative to SAVR in unsuitable transfemoral access? Transcarotid versus surgical aortic valve replacement for severe AS Marisa Avvedimento @delportilloJH Sid Mengi, MD, MRCP Pedro Cepas #AHAJournals ahajrnls.org/4iCJPEU

#TAVR poll Patient with TAVR 11 years ago, S3 26 mm, MG 41 mmHg. CT shows HALT, leaflets no calcification. What is your anticoagulant of choice?

Are we officially changing US nomenclature from #TAVR ➡️ #TAVI

Treat the valve AND the myocardium when facing severe AS+amyloidosis. Both AVR and tafamidis independently ↓ mortality Dual therapy=best outcomes w/ similar survival to lone AS+AVR. Dual pathology is common (~13%) warranting RCT. tinyurl.com/2zmpht8x Bravo Thomas Treibel! 👏🏻