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A beautiful cryo-EM study of different oligomeric assemblies of a bacterial RNP complex from Ben Luisi's group

Architectural principles for Hfq/Crc-mediated regulation of gene expression dx.doi.org/10.7554/eLife.…

#bacterial #viruses hijack the #bacteria #metabolism, including #RNA turnover. Our #Review on #phage #host #transcription mechanisms in Annual Reviews #Virology : bit.ly/2Qcvkvc thanks #Editor Graham Hatfull for the quirky title idea. #microbiology #protein #biotechnology

Using Tomo5 for cryo-ET data collection but want to use Warp and M later? mdocspoofer makes fake mdoc files for you so you can plug your data into Warp! Written for TomDendooven github.com/alisterburt/md…

New preprint from 7 labs! We’ve joined the fight and looked at the inhibition of a highly conserved structured RNA element in SARS-CoV-2. biorxiv.org/content/10.110… 1/5

Online Now: Structures of B. subtilis Maturation RNases Captured on 50S Ribosome with Pre-rRNAs dlvr.it/RhX69H

This is exactly what #teamtomo needs. Nice work Alister Burt et al. 💪💪 Next step is to add fiducial-less tilt-series alignment to the front and deep learning picking and segmentation to the back. biorxiv.org/content/10.110…

Hey #teamtomo - our lab (Barford Group @MRC_LMB) are looking for a postdoc to join us in our efforts to understand kinetochore structure and chromosome segregation! Retweets appreciated, DMs very much open for informal enquiries about life here mrc.tal.net/vx/mobile-0/ap…

How does bacterial RNA #chaperone #Hfq regulate numerous different mRNAs and processes? #CryoEM by TomDendooven Ben Luisi Cambridge University and collaborators shows assembly into distinct polymorphic #ribonucleoprotein complexes as basis embopress.org/doi/10.15252/e…

Great work by an equally great colleague! Structure of the Ndc80-Dam1 complex bound to microtubules, with important implications for how Error Correction regulates chromosomes segregation. Glad I could contribute!

Happy to see one of the last pieces of my PhD work published! Very lucky to have awesome TomDendooven as a partner in crime Also many thanks to Alister Burt, Dom, John, David and Rappsilber laboratory

When I joined David Barford's group @MRC_LMB it was with the goal of using my cryo-ET and computational skills to help them understand funky biology. I joined TomDendooven and Stanislau Yatskevich's efforts to average the native gamma tubulin ring complex (γTuRC) from tomograms of SPBs

Over 34 years ago, MRC-LMB Cell Biology's John Kilmartin first purified yeast spindle bodies with their attached spindle microtubules. Still going strong he has now collaborated with David Barford's lab to reveal how gamma tubulin nucleates microtubules.

Ever wondered if nuclear pore architecture and function changes during germ cell differentiation? In human spermatogenesis it does, and radically!! Check out our first lab preprint Ália dos Santos et al! biorxiv.org/content/10.110… Piotr Kolata Alister Burt TomDendooven @MRC_LMB