The hottest new programming language is now biology 😉 #esm3

An artificial intelligence model that speaks the language of proteins has been used to create new fluorescent molecules go.nature.com/4bCoMhk

After we trained ESM3, we were excited to see it could respond to complex prompts, which greatly improved with scale. While scaling has been driving advances across AI—in biology it has been largely underestimated. Article by Ewen Callaway for nature: nature.com/articles/d4158…

Thank you so much for hosting me! I had a lot of fun presenting and meeting you all.

The ESM3 package was updated on pip. We fixed an issue with iterative structure prediction. Expect to see major improvements after doing: pip install -U esm

Introducing ESM Cambrian. Unsupervised learning can invert biology at scale to reveal the hidden structure of the natural world. We’ve scaled up compute and data to train a new generation of protein language models. ESM C defines a new state of the art for protein

One of my favorite plots ❤️ x.com/alexrives/stat…

Evolutionary Scale · ESM Cambrian: Revealing the mysteries of proteins with unsupervised learning evolutionaryscale.ai/blog/esm-cambr…

Whoa! When a large language of life model generates a protein equivalent to ~500 million years of evolution. Science Magazine science.org/doi/10.1126/sc… Thomas Hayes Roshan Rao EvolutionaryScale Arc Institute UC Berkeley

We're thrilled to present ESM3 in Science Magazine. ESM3 is a generative language model that reasons over the three fundamental properties of proteins: sequence, structure, and function. Today we're making ESM3 available free to researchers worldwide via the public beta of an API

Sign up for Forge, our new API for biological intelligence, now in public beta: forge.evolutionaryscale.ai

ESM3 paper now out in science! Give it a read. We're also releasing widespread API access - commercial okay. No code UI tool to generate your own proteins! And compute grants for academic users doing cool projects.

We’re also announcing an ESM3 compute grant pilot program for applications at the scientific frontier. ESM3 can enable creative applications of protein engineering from drug design, to green chemistry, and materials science. Please apply on Forge if your research could benefit

An #AI model created to design proteins simulates 500 million years of protein evolution in developing a previously unknown bright fluorescent protein. Learn more in a new Science study: scim.ag/4jhJ9Wa

This is the first generative protein language model trained on three protein features: sequence, structure, and function. Using GFP as a test case, the model generated a bright functional protein with low sequence homology to known proteins – estimated to be equivalent to a

Researchers have developed a deep learning protein language model, ESM3, that enables programmable protein design. Learn more in this week's issue of Science: scim.ag/4b5IlQu

Today CZI is announcing an unprecedented new scientific initiative to build the future of AI-powered biology. I am joining CZI to lead this initiative as Head of Science, and the EvolutionaryScale team is joining forces with Biohub. This is the first large scale scientific

I am beyond excited that EvolutionaryScale will be joining @Biohub! This brings together our strengths in AI research with frontier bio capabilities.

Our amazing team at EvolutionaryScale are joining forces with CZI to train some big models at Chan Zuckerberg Initiative ! I'm really excited to be on this journey. I'm extra excited to open source some models again for the scientific community. We're cooking some good stuff :)