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Super resolution microscopy Airyscan images of Paraspeckle - taken here in Sheffield. Paraspeckles are ribonucleoprotein bodies found in the cell nuclei. These structures play a role in regulating the expression of certain genes by nuclear retention of RNA.

Exciting PhD opportunity!! Looking at The role of post-translational protein modifications (PTMs) in the regulation of RNP biomolecular condensates in health and motor neuron disease. Supervised by TS, Mark and Caroline. Follow the link! findaphd.com/phds/project/t…

Job Advert: Post of Postdoctoral Research Associate within TS Lab. The overarching goal of this project is to provide novel insights into the regulation of disease-relevant RNA granules. Follow the link for more info jobs.ac.uk/job/CYE906/res…

Professor Dame Pamela Shaw has dedicated her life and a remarkable career to investigating and treating Motor Neuron Disease (MND). She features in today’s The Yorkshire Post, discussing why she is optimistic that there will one day be a cure. yorkshirepost.co.uk/health/motor-n…

Are you interested in #mitochondria in Hereditary Spastic Paraplegia & drug discovery? Then we have the position for you. jobs.ac.uk/job/CYM426/res… We are looking for an enthusaistic postdoctoral researcher to join the team on this exciting translational project Neuroscience Institute

Celebrating TS’s birthday at our weekly lab meeting 🎂🎉🎊🍾

On #GlobalMNDAwarenessDay we are sharing facts about motor neurone disease research and the challenges that need to be and are starting to be overcome in the fight against #MND. We dare you to share these facts, start conversations and learn more. #MNDoverMatter

On #ResearchAppreciationDay we would like to thank the dedicated researchers from all around the world who are working tirelessly in the fight against #MND #ALS. We are stronger together. 💙 🧡 #WithoutResearchItsJustGuesswork

The future of motor neurone disease research looks bright ✨ Last week we brought early career researchers, senior researchers and people living with and affected by #MND to connect, collaborate and develop skills. 🤝 Hear what attendees thought of the event ⬇ #MNDEnCouRageUK

Brittany, our PhD student presenting at MND EnCouRage event. Great experience meeting other ECRs working on ALS and interacting with ALS patients 🧬👨‍⚕️

Trying to get the best pose 😅 #SITraN #TSLab #UoS

It was great participating in ENC ALS 2023 meeting in Barcelona last week. Some of our lab members presented their posters and it was a great opportunity to network with ALS researchers from across Europe MND Association MND Scotland Neuroscience Institute

Last day of Med School Research Meeting, great poster presentations by Cara and Jess 🧬🌌

That was Jess, our technician’s last day at work.. wishing her all the best as she goes traveling to South America ✈️

Soak a Scientist 2023 South Yorkshire MNDA It was great fun fundraising at Endcliffe park yesterday, it supports our essential MND research Neuroscience Institute MND Research

Tim Shone's advocacy in the #MND fight is an ongoing inspiration 💜 His remarkable efforts raised £178,000 for research at your University, giving hope to future #MND sufferers. Learn about the legacy Tim has left: buff.ly/3scXuNI #ALS #SheffieldAlumni

Cara and TS attended the 1st TDP-43 conference in Trieste last week and presented some of the most recent unpublished data on the role of TDP-43 in paraspeckles (talk and poster). 3 days of TDP-43 biology - what can be better?..😀👩‍🔬

Farewell to Emma from Archa's lab, University of Western Australia and temporary goodbye to Rachel who is off to maternity leave. Rachel has submitted her fellowship applications and can now relax (until the baby arrives at least!).

2nd Neuroscience Institute ECR Symposium. Emily, Georgia, Brittany and Ved presented posters and flash talks on their PhD projects. Well done!! 🎉 #Universityofsheffield #neuroscienceinstitute Neuroscience Institute Faculty of Health | University of Sheffield

Excited to announce our latest publication in Science Advances, "M6A-dependent RNA condensation underlies FUS autoregulation and can be harnessed for ALS therapy development | Science Advances" 🎉🔖🧬🔬 Give it a read! science.org/doi/10.1126/sc…