Our story on NLRP3 priming is now out in Immunity after 5 years in the making. We found that IKKβ primes the inflammasome by recruiting NLRP3 to the trans-Golgi network. This allows the NLRP3 inflammasome to form independently of NEK7. Summary👇 authors.elsevier.com/c/1g5G03qNrUqG…

Sugestie jak podnieść poziom i znaczenie polskiej nauki w świecie dla Przemysław Czarnek Ministerstwo Edukacji i Nauki i KRASP A) bez dodatkowych kosztów stałych 1) zadbać aby wszystkie konkursy o zatrudnienie i awanse były otwarte, uczciwe i rzetelne oraz premiowały doskonałość naukową i dydaktyczną

#DIK #sepsis kills >5 million people yearly & is the #1 cause of death in hospital critical care units? Pablo Pelegrin & team Fundación FFIS developed a mobile device to quickly detect complications in patients. 👉 bit.ly/3Rj6RnF #immunology #ai @IMIB_Arrixaca @Cordis_EU

I need to raise awareness about an important point in #scRNAseq data analysis, which, in my opinion, is not acknowledged enough: ‼️In practice, most cell type assignment methods will fail on totally novel cell types. Biological/expert curation is necessary! Here's one example👇

Imagine being a fly on the wall when Albert Einstein met Irène Joliot-Curie. The two Nobel Prize laureates met in March 1948 at Einstein’s home in Princeton, New Jersey, USA. What the two of them talked about is unknown, but Marie Skłodowska Curie might have been mentioned.

Why do bears not suffer from thrombosis during hibernation? The Bear Necessities for Anticoagulation. Amazing study by Tobias Petzold et al science.org/doi/10.1126/sc… youtube.com/watch?v=6BH-Rx…

How have #MiceInResearch advanced medical science? Mice have been used in almost all research areas to test the safety of drugs & treatments. They have also been essential to improving our understanding of how diseases progress inside the body. #AnimalResearch #ConcordatOpenness

This is going to be a special event, not only because of the scientific level of the Congress

New baby on the board! #facs #cytometry #flowcytometry #cellsorting Beckman Coulter

We are excited to present the CIRS-LAS tool for improving animal studies in the WS "Animal models in sepsis and COVID-19"at #Sepsisupdate2023. Join us for this wonderful session put together by Marcin Osuch and Tomasz Skirecki on improving animal models for infection research.

Cant wait to join one of the best #sepsis focused meetings in the world to co-chair the animal research WS with @osuchm. Many thanks to Frank M. Brunkhorst for invitation!

A great place for a Congress to go to! ESS

"If we lose patients to bleeding we lose them early..." Herbert Schöchl, MD on the state of the art in Trauma-Induced Coagulopathy TIC and bleeding management in polytrauma. Goosebumps 😀 #ESS2023 ESS LBI Trauma #TIC #Blood

40 years of ESS - Down the Memory Line by Borna Relja and Andrea Szabo with the round table with the Past Presidents

Great X-mas present! Proud of this collaborative effort with my fellow @egis_sepsis members.

Thank you Critical Care Reviews for sharing our summary of the aspect of compartnentalization of the immune response in sepsis. Still many unanswered questions are emerging. Thanks Chousterman Benjamin and the great Jean-Marc Cavaillon👍

Happy to share our research showing that #SARS-CoV-2 variants differentially activate human macrophages and specifically #inflammasome: sciencedirect.com/science/articl…

Pleased to see our manuscript on the role of #SARSCoV2 viroporins in the activation of NLRP3 #inflammasome and induction of IL1a online. A great collaborative work! rdcu.be/dFJgo

Its a great privilege to publish in such distinguished journal that started in 1896! The American Journal of Pathology! Thank you for a productive editorial process🙏 #ards #stromal cells #regeneration #criticalcare

Cell-cell interactions are key for the pathogenesis of bacterial infections, Kudos to the authors