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My deepest thanks to the Sherman Prize team for the special day at Advances in Inflammatory Bowel Diseases - for myself and the 2023 co-honorees Andres Yarur and Corey Siegel. Appreciative of all the special touches. Thanks to all for the kind words and well wishes #IBD Cleveland Clinic Lerner Research Institute

Interested in how #immune cells develop?  Learn more about Dr. Jayati Basu’s Cleveland Clinic Lerner Research Institute Cleveland Clinic cutting edge research as she discusses #infection #cancer #inflammatory bowel disease and T Cell impact. #ImmuneCells #SignalingPathways Jayati Basu tinyurl.com/4dpznyv2

The Cleveland Clinic Lerner Research Institute is a terrific environment to launch your career as a scientist.  Brian Gaudette, PhD, who recently joined our team in Inflammation & Immunity, talks about his experience with mentorship. Penn Medicine Emory University #BCells Cleveland Clinic tinyurl.com/24ap62ux

Spotlighting Samantha Wightman Ph.D. this month/Post Doc in Yuxin Wang’s lab investigating cytokine signaling pathways/Dr. Wightman believes a good scientist is very skeptical/has strong critical thinking skills to solve problems / Keep solving! @CleClinicLCM Northern Michigan University Case Western Reserve

Outstanding mentorship programs are the hallmark @ClevleandClinic Cleveland Clinic Lerner Research Institute.  Listen to Kevin Newhall MD PHD candidate/studying | 🐆 discuss his physician-scientist training experience Cleveland Clinic Children’s.  #CleClinicChildrens Manuel Braga Neto MD, PhD Jacob Kurowski tinyurl.com/dffztd77

Wonderful to host Zia Rahman from Thomas Jefferson University. Fantastic seminar on #BCells #GerminalCenters Cleveland Clinic Lerner Research Institute Cleveland Clinic and great dinner conversations at Zhug with J. Michael Stolley #BrianGaudette

Our paper identifying retrotransposition as a potential driver of microcephaly is now out in Nature Communications. doi.org/10.1038/s41467…. This was a combined effort of many -so proud of the team! Congrats Mary Jo and Bert! Cleveland Clinic Lerner Research Institute

Excellent new study Nature Communications led by Michelle Longworth, PhD, finds retrotransposable elements as new cause of Microcephaly/shows connection between RTE-repressive functions of condensins/role promoting normal brain development. Cleveland Clinic Lerner Research Institute Michelle Longworth, Ph.D. tinyurl.com/26p5tvsh

Why are organ transplant grafts with high ischemia prone to acute injury? The answer is here and involves Il-12 and IL-15 signaling between graft and endogenous adaptive immune cells! /see excellent paper by the Cleveland Clinic Lerner Research Institute I&I transplant team #Immunology tinyurl.com/5n6wc7br

This month we are spotlighting I&I’s José Ignacio Valenzuela, MD, a post doc in the  Valujskikh lab honing his skills in microsurgery, specifically-heart transplantation & driving research toward new therapeutic interventions.  Well done Dr. Valenzuela!  @CCRLI #heart #transplant

Really looking forward to CWRU School of Medicine & Dept. of Inflammationn & Immunity Cleveland Clinic Lerner Research Institute / Annual Immunology Retreat tomorrow & hearing keynote speaker Avery August, PhD, Avery Judkins @Cornell/Ecker Memorial Lecture. Great space for retreat @cbgarden #immunology #CornellResearch @Cornellvet

Dr. Andrea Schlegel leads an impressive & dynamic organ transplant team investigating the role of mitochondria in liver transplantation.  Opportunity to join a phenomenal team!  Cleveland Clinic Lerner Research Institute Cleveland Clinic  #transplantation  #immunology

This month’s I&I spotlight is on Sepideh Khazaie, MD, Post Doc/Baldwin lab. Dr. Khazaie transitioned from/clinical research fellow/sleep medicine/to studying basic science--driven by her aspiration to become a physician-scientist. Well done! #inflammation Cleveland Clinic Lerner Research Institute Sepideh Khazaie, MD

Next week we will celebrate the remarkable career of my colleague Ganes Sen, PhD/retiring after 36 years of service Cleveland Clinic Cleveland Clinic Lerner Research Institute -Dr. Sen’s impressive career as a leader in interferon research has spanned over five decades/Wishing you all the best in your next chapter!

Congratulations to my colleague Carol de la Motte, PhD – celebrating her leadership/exceptional research career in intestinal health & disease & years of service Cleveland Clinic Cleveland Clinic Lerner Research Institute. All the best on your retirement and next chapter!

A new study led by Srinivasan Dasarathy, MD, Cleveland Clinic Lerner Research Institute/PNASNews National Academy of Sciences/ shows the ammonia transporter Rhesus blood group-associated B glycoprotein can activate NfKb through Myd88 tinyurl.com/mwcx7y4p

New findings in Hepatology AASLD have identified 2 new loci with previously unknown correlations to Alcoholic Liver Disease/highlighting the etiology between liver diseases & unique origins of Alcohol-Associated Hepatitis #liver #hepatitis Cleveland Clinic Lerner Research Institute tinyurl.com/2asrmsrh

Good luck to my I&I colleagues Dr. Gail Cresci &  Dr. Michelle Longworth (& her son Sam) training to ride for the Velosano! / supporting life-saving cancer research. @bikeVelosano Cleveland Clinic Lerner Research Institute #VeloSano #ClevelandClinic give.velosano.org #100PercentForTheCure Michelle Longworth, Ph.D.

Thank you to my friend & colleague Skip Virgin, MD, PHD, for a tremendous guest lecture Cleveland Clinic Lerner Research Institute Cleveland Clinic today.  Your insights on training for AI drug discovery & translational science were thought provoking. Gates Open Research Gates Foundation WashU Medicine #UTSW #AI

Great insights at today’s I&I seminar on ‘Gut-Liver Axis Calibrates Intestinal Stem Cell Fitness’ by guest speaker ChuanWu_Lab, hosted by Thaddeus Stappenbeck, MD, PhD . Cleveland Clinic Lerner Research Institute Cleveland Clinic