⭕️📄 Watch out: here it comes the "recycler"! Zhou and collaborators propose that SNX4, SNX5 and SNX17 form a novel complex that identifies and retrieves (assisted by the dynein-dynactin complex) autophagosomal membrane components from the autolysosome. nature.com/articles/s4155…

❤️ this tweet to find out what guesting with IHG can get you. #GuestHowYouGuest at any of IHG's 6,000 global hotels and earn points with the NEW IHG One Rewards.

Amazing work from my lab mate Taryn Olivas! Taryn employs a combination of powerful biochemical techniques - membrane fractionation and styrene maleic acid extraction - to directly demonstrate that ATG9A and LC3B reside on the same membrane. Congratulations Taryn and fellow authors!

hey all, we would love to see some great cell biologists apply to the new Yale Science Fellows program! Pass the word around and note: 𝘼𝙥𝙥𝙡𝙞𝙘𝙖𝙩𝙞𝙤𝙣 𝘿𝙚𝙖𝙙𝙡𝙞𝙣𝙚 𝙣𝙤𝙬 𝙚𝙭𝙩𝙚𝙣𝙙𝙚𝙙 𝙩𝙤 𝙉𝙤𝙫𝙚𝙢𝙗𝙚𝙧 1𝙨𝙩!!!

Important news re. journal Aging Cell. Please distribute.

Come hear my talk on Monday at 11:15 in room 201 where I’ll share my work demonstrating ATG2A mediated lipid transport at a phospholipid monolayer, and come find my poster at B432 #CellBio2022

New transatlantic preprint🥳! A sensor-modulator subunit directly regulates the Atg1 kinase complex during phosphate starvation-induced #autophagy. Wonderful work from Angelina Gross and colleagues: biorxiv.org/cgi/content/sh…

Check out this fantastic study from Bulat Ramazanov and @LabVon! Bulat shows beautifully the necessity of calcium flux across the ER-TGN contact site to facilitate Cab45 mediated cargo efflux from the TGN. biorxiv.org/content/10.110…

Truly excited that our collaboration with Cantley Lab and YaffeLab, led by the mighty Jared Johnson and the unstoppable Tomer M. Yaron-Barir, to map substrate motifs for the Ser/Thr kinome is now out! Literally a project that spanned decades. nature.com/articles/s4158…

Today, I’m thrilled to share a preprint of our work describing SPEAR, a sparse supervised #Bayesian factor model for #multiomic integration: biorxiv.org/content/10.110… Follow along this #tweetorial to learn about SPEAR! Yale CBB (1/🧵)

The Baskin Lab strikes again! What a wonderful toolkit to study lipid transport in living cells. Fantastic!

Congratulations to my fantastic lab mate, Taryn Olivas! This compelling study beautifully demonstrates the residence of the sole transmembrane protein in the core autophagy machinery, ATG9A, on both progenitor vesicles and autophagosome membranes.

Check out this fantastic work from my lab mate, Justin Korfhage Justin Korfhage! Justin demonstrates that ATG2A is capable of transporting lipids between phospholipid monolayers and bilayers and demonstrates that this activity is necessary for efficient lipid droplet regulation.

Cholesterol-dependent homeostatic regulation of very long chain sphingolipid synthesis rupress.org/jcb/article-ab…

Please check out our (Bewersdorf Lab) latest work on #FLASHPAINT published in Cell. #FLASHPAINT builds on #DNAPAINT and allows for fast and fluorogenic, highly multiplexed super-resolution imaging. cell.com/cell/fulltext/…

SPEAR: A supervised bayesian factor model for the identification of multi-omics signatures academic.oup.com/bioinformatics…

I'm excited to share a part of my PhD work with you! In this paper, we show that ATG2A localizes to rab1a containing early secretory membranes during autophagosome biogenesis. Following ATG2A/B deletion, these membranes coalesce with the rest of the biogenesis machinery.