
Stephen Sykes
@thesykeslab
Sykes Lab focused on the study of healthy and malignant hematopoiesis.
ID: 1129133089375031297
https://thesykeslab.com 16-05-2019 21:14:41
152 Tweet
492 Followers
199 Following


Thrilled to share our latest work in Scienceβ¦β¦. We discovered a novel non-mobilizable HSC pool. I really appreciate the huge support from β¦Uli Steidlβ© β¦Britta Willβ© and all the co-authors. I hope Paul is smiling at all of us from above! science.org/doi/10.1126/scβ¦

I am very excited to share that our manuscript from @Ferraro_lab WashU Medicine is out in Clinical Cancer Research . We show through several orthogonal methods the changes that mutant Myc orchestrates in the hematopoietic compartment resulting in AML. aacrjournals.org/clincancerres/β¦

This week selection of papers in myeloid leukemia biology and therapy is out! In a shameless self-promotion the pick of the week is our group paper on SCD inhibition in AML! Enjoy it biomed.news/bims-tremyl/20β¦ Thanks as always Bims: Biomed News Below the pick nature.com/articles/s4137β¦



T-48 hrs until the start of our 3rd Annual @WashUHeme Retreat! Excited to hear about the latest research from our trainees & faculty, and especially thrilled to welcome Alisa Wolberg for the Evan Sadler Special Lectureship! #hematology WashU Medicine Department of Medicine


My very talented graduate student Nicole Arellano wrote a highlight in eLife - the journal on beautiful work by first author Rebecca Warfvinge that links cellular heterogeneity in CML stem cells to TKI response. Check both out below! elifesciences.org/articles/92074 elifesciences.org/articles/103775

Very fun and productive collaboration with Bobby Bowman & Ross Levine modeling mutation order and oncogenic dependency in AML. I've always wanted to do this but we were previously limited by available tools... this is a huge step forward! authors.elsevier.com/c/1k4rd5TA51hPβ¦

Excited to share our latest work published today in Science Immunology and featured on the cover! This study demonstrates that thrombospondin-1 (Thbs1) is a driver of hematopoietic aging and that targeting Thbs1 suppresses inflammaging and restores systemic and HSC healthspan.

Delighted to see our CLN1 & CLN2 Enteric Nervous System gene therapy paper published in Science Translational Medicine today! Big team effort with many great colleagues Heuckeroth Lab WashU Medicine Pediatrics & directly inspired by Batten families BDSRA Foundation NINDS Tracy VanHoutan science.org/doi/10.1126/scβ¦



Thrilled and honored to have received an Fondazione AIRC per la ricerca sul cancro StartUp grant to support my leukemia research here at UniversitΓ di Parma !


#StandUpForScience2025 Siteman Cancer Center WashU Medicine Division of Oncology WashU Medicine DONTβT CUT SCIENCE FUNDING!!!

