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Drs Godfrey Mayoka John Woodland & Kelly Chibale highlight Alexandra Gould Leann Tilley & colleagues’ recent Science Magazine paper in this Spotlight: Thwarting protein synthesis leads to malaria parasite paralysis. UCT H3D Discover JKUAT authors.elsevier.com/a/1fPle5Eb1xBg…

Adenosine sulfamates: Next generation of #antimalarials. Audrey Odom John MD PhD @SeshMDPhD highlight recent work of Leann Tilley Science Magazine uncovering a class of nucleoside analogs that selectively hijack & inhibit tyrosine tRNA synthase of #malaria parasite cell.com/cell-host-micr…

A thoughtful commentary on our nucleoside sulfamate antimalarial work and an insightful reflection on the history of nucleoside-based anti-infectives. I loved reading about the contributions of Gertrude Elion. cell.com/cell-host-micr…. Audrey Odom John MD PhD @SeshMDPhD #malaria

Congratulations Cameron on a great PhD oration today!! Bio21 Institute UniMelb MDHS Hayley Newton

PLACEHOLDER! MPG Symposium is being held late this year due to the exciting addition of combining with RACI VIC #CHEM2023. Whole meeting will run Tue 23rd Oct - Thurs 25th Oct. Keep your eyes peeled for more info... #protein

We have a position open in the lab to take care of our SEMs and EDS workflow. ⁦Bio21 Institute⁩ ⁦University of Melbourne⁩ Details : Technical Officer, Scanning Electron Microscopy jobs.unimelb.edu.au/en/job/913307/…

Excited to see our #malaria pre-print dx.doi.org/10.21203/rs.3.…. An amazing collaborative effort from many sites across the globe to define the mechanism of action of a promising new class of reaction-hijacking inhibitors, targeting a tRNA charging enzyme in malaria parasites.

Open for registration. RACI VIC and MPG joint conference. To be held RMIT University. Register now CHEM 2023 / MPG (raci.org.au) and submit abstracts by 22nd Sept forms.gle/Xr3yp8xHeVnboS…. Lots of speaking slots for #students and #ECRs

I am pleased that our review entitled: Targeting Aminoacyl tRNA Synthetases for Antimalarial Drug Development, in Annual Review of Microbiology is now available Open Access. doi/10.1146/annurev-micro-032421-121210. Winzeler Lab Griffin Lab IRB Barcelona Malaria Papers

Excited to share our reviewed preprint on a TRAP transporter doi.org/10.7554/eLife.… in eLife - the journal where an unexpected dimeric assembly was used to obtain a high-resolution structure. Big thanks to Michael Currie, @_jamesdavies and Dobson Lab, along with our fantastic collaborators!

Congratulations Riley! Was quite a journey to get this out there - a huge credit to Riley for his hard work and determination.

Really proud of this work published today understanding the assembly of the IL-11 signalling complex, dynamics of the gp130 receptor subunit, and how to inhibit IL-11 signalling. A brilliant collaboration! @riley_dm, Eric Hanssen, @PutoczkiLab. doi.org/10.1038/s41467…

Online Nature Communications! Using #NMR, #HDX and #RapidKinetics, we showed induced-fit underlies neurotensin receptor 1 activation by neurotensin peptide! We posit that induced-fit is far more prevalent in #GPCRs than previously thought! nature.com/articles/s4146…

Great to see this beautiful work published today. And wonderful to be part of the global team advancing this amazing program! nature.com/articles/s4146…

Great fun to work with Prof Natalie A Sims reflecting on new insights from the Garbers lab doi.org/10.1111/febs.1…, and open questions still to be answered surrounding craniosynostosis-associated variants in the IL-11 signalling machinery! febs.onlinelibrary.wiley.com/doi/10.1111/fe…

Don't miss out on your opportunity to attend and participate in Biomolecular Horizons 2024, held in Melbourne!  YOUNG SCIENTIST PROGRAM- LAST CHANCE- application deadline extended to Friday 8 March Biomolecular Horizons 2024 bmh2024.com/young-scientis…

SAVE THE DATE! Excited to announce the 22nd Melbourne Protein Group Symposium will be hosted at WEHI on Thursday 11th July 2024. Spread the word to other graduate research/ student colleagues. Details of keynote speakers and abstract submission to come.

💀The Garbers team @MHH_life characterise two clinically relevant variants in the #Interleukin-11 receptor gene & their roles in premature closure of 💀 bone sutures: 💀 buff.ly/3WgYjC7 🔆 Commentary by Prof Natalie A Sims: buff.ly/3Wc07wh #craniosynostosis

Excited to see our study published in PLOS Pathogens. Multi-stage activity & single oral dose killing of P. falciparum in vivo. Structural basis for improved potency and selectivity of this reaction-hijacking inhibitor are revealed. doi.org/10.1371/journa…