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New paper from my lab! Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesis: rdcu.be/eh1Nb Complementary to new work from Steven Chan & George Vassiliou as described by Peggy Goodell: nature.com/articles/d4158…

Congrats to Kira Young who spearheaded this work & all contributing authors. This was a fun (and long!) collaboration with Marc Mansour, Grant Challen, Eric Pietras, Kelsey Fisher-Wellman, Keisuke Ito_Lab & Steven Chan. Supported by NIH, EvansMDS & The Leukemia & Lymphoma Society .

So happy for you both, Kira Kira Young and Jen Jennifer Trowbridge, & Steven on the paper publication! Such a joy working with you and team. Claudia Claudia Morganti and I are thrilled to be part of this amazing study on mitochondrial activity in CH-mutant HSPCs! EinsteinSCI

Excited to share the Peggy Goodell News&Views on 3 exciting studies by Vassiliou Lab, Chan Lab, and Jennifer Trowbridge in nature and Nature Communications, showing that blood stem cells with mutant #DNMT3A (major driver of Clonal Hematopoiesis) depend on enhanced mitochondrial respiration ⬇️

Always bittersweet when trainees leave the lab. Today marks the last day for our PREP student, Carlos Carlos Hurtado Muñoz 🇨🇴, as he is moving on to the MSTP program. So proud of your growth—wishing you all the best for the future! Congratulations! EinsteinPhD Albert Einstein College of Medicine - Official EinsteinSCI

Had a lovely warm-up discussion last night with Jean-Emmanuel Sarry Lab during his visit to NY! Excited to kick off collaborative efforts and can’t wait for his seminar at Albert Einstein College of Medicine - Official Blood Cancer Institute today! Ayşegül Erdem EinsteinSCI

Had a wonderful dinner with young Japanese researchers from Albert Einstein College of Medicine - Official & a guest clinical resident from Japan! Truly inspired & encouraged by all of you. Congrats on your amazing achievements—excited to see your continued growth and future successes! Wenjun_Guo EinsteinSCI

Our collaborative study with Keisuke Ito_Lab on how Tet3 regulates embryonic & adult HSCs is published in HemaSphere Journal (IF = 11.9) journal.Congrats to first authors Harmony & Claudia. Hope you find it interesting. Albert Einstein College of Medicine - Official EinsteinSCI EinsteinPhD EinsteinGenetics onlinelibrary.wiley.com/doi/full/10.10…

So excited our study is published in HemaSphere Journal (IF = 11.9)! Truly a joy working with Harmony, Meelad Dawlaty, and the team, plus Claudia Morganti, Chie & I are thrilled to be part of this exciting research on TET3’s role in HSC homeostasis. Looking forward to more collaborations! EinsteinSCI

New paper from our lab! In this study, we show that AML cells critically depend on LDHA to maintain their NAD+/NADH balance. Congrats to first author Ayşegül Erdem and all co-authors! cancerandmetabolism.biomedcentral.com/articles/10.11…

Our trainees had a truly enriching experience at #KUHRTN2025 at Emory School of Medicine, Atlanta! They gained insights into career development, received valuable advice, and enjoyed connecting with field leaders and peers (@KUHR_Trainees) from across the country. bit.ly/3H529IZ

NYCTrainKUHR trainees were amazing at #KUHRTN2025! They presented their research beautifully, received insightful feedback, enjoyed engaging small group discussions, and truly appreciated the power of networking and collaboration! bit.ly/4k2doQY

NYCTrainKUHR team joined inspiring talks on mentoring & program growth, connected with other @KUHR_Trainees programs, and took part in mentor–mentee sessions. Huge thanks to ATLANTIS - KUH Research Training Program for the fantastic organization!! #KUHRTN2025

We are deeply saddened by the passing of Dr. James Till, one of the fathers of stem cell science. His research alongside Dr. Ernest McCulloch at UHN's Princess Margaret Cancer Centre changed the course of cancer research and paved the way for regenerative medicine.

Excited to see the first commentary in Exp Hematology (ISEH)! Kudos to Aishwarya Aishwarya Krishnan, Linde Linde Miles and Grant Grant Challen for highlighting recent papers in Elsevier Hematology on cell-extrinsic factors in Tet2-mutant clonal hematopoiesis. bit.ly/4k3pEAI

Bittersweet to see trainees move on, but so proud of our amazing Lidiane (Lidiane Torres) as she starts her next chapter! Your passion for neutrophil biology & sickle cell disease has inspired us all. Keep shining—we can’t wait for more chances to team up again! EinsteinSCI

Another heartfelt farewell to our collaborator Dr. Deepa Manwani, Montefiore Pediatrics Hematology, as she heads to St. Jude Research (led by our friend Dr Mitch Weiss) after years of dedicated care & research in sickle cell disease. We’ll miss you, Deepa—here’s to bridging Memphis & NY!

Catching up with my @HarvardMed postdoc buddies instantly takes me back! Had such a lovely dinner in NY with my close, same-age friends Shingo Shingo Kajimura Lab HHMI & Hiro Hiro Morishita. Thank you for always inspiring me with your science and for a friendship that never changes!!