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ESCMID/EUCIC clinical guidelines on preoperative decolonization and targeted prophylaxis in patients colonized by multidrug-resistant Gram-positive bacteria before surgery clinicalmicrobiologyandinfection.com/article/S1198-…

Favorable Antiviral Effect of Metformin on SARS-CoV-2 Viral Load in a Randomized, Placebo-Controlled Clinical Trial of COVID-19 bit.ly/3WRv3ka

Passive immunity from mother to offspring is important for protecting against infections early in life but can also hamper immune responses to vaccines in newborns. This is why some vaccines are not given as early after birth as we'd like (ex measles). New interesting work from

1/ We are excited to share our report in #JEM that about 10% of severe tick-borne encephalitis (TBE) cases, triggered by the TBE virus (TBEV), are due to pre-existing auto-Abs neutralizing type I IFNs (doi.org/10.1084/jem.20…).

The sky is blue and yet another cooling RCT is negative 👇🏻 But. It doesn’t matter, people will still do it. I’m not sure there is an intervention more resistant to negative trials.

🔥New antiviral (Ziresovir) in hospitalized infants with RSV Infection. nejm.org/doi/full/10.10… -0,8pts in the 12pt Wang bronchiolitis score at day 3. I am not impressed. In fact, most antivirals for acute infections suck. Let's rather invest in vaccines! 💉

Must read for all people in training for public health preparedness and response: how NOT to handle an unexplained human case with a potential pandemic pathogen. More people in contact with the case symptomatic, not tested statnews.com/2024/09/27/bir…

I ❤️ it, we need more of this stuff: pragmatic, open-label RCTs with meaningful primary outcomes. 🇩🇰 leads the way...

A seven-day course of antibiotics for hospitalized patients with bloodstream infections is just as effective as a 14-day course, according to new findings presented at #IDWeek2024. Learn more: idsociety.org/news--publicat…

More is not always better. Adding vancomycin to cefazolin as surgical prophylaxis in patients undergoing arthroplasty does not improve outcomes in patients not known to be MRSA colonized. Outcomes WORSE for knee arthroplasty. Just don't. nejm.org/doi/10.1056/NE… #IDWeek2024

Amazing to see no major differences in ANY of the different pathogens in BALANCE RCT #shorterisbetter

Great news. More options for RSV prophylaxis coming soon and looking good!

Comprehensive study on unconditional cash transfers. TLDR: "Overall, the negative effects on labor supply do not appear to be offset by other productive activities" More in the well-written🧵👇

HPV vaccines offer a rare opportunity to effectively eliminate cervical cancer. By taking this opportunity, it’s possible to save the lives of hundreds of thousands of women each year.

Clinical research as it is supposed to be 👇

Hello everyone! Dear #IDtwitter! I also have an account on the other side 💙, please follow me there if you want to keep in touch: Tilmann Schober.bsky.social. I will stay here for a while, but will not not be as active

I can’t believe no one’s made a gif of this one yet. I’ll quote the great 20th century philosopher, Dirty Harry. “Excuses are a lot like assholes. Everybody has one.”