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IPI's Founder timothy springer on NPR today. For #CovidVaccine, Derrick Rossi and Moderna scientists gave mRNA “fake passports," paving the way for the upcoming end to Covid 19 wbur.fm/2K5myk5

IPI Executive Director Alex Burgin, weighing in on monoclonal antibodies: "Our mission is to enable others...to accelerate science, and if that results in new therapeutics, that is fantastic." bit.ly/3i4GIaq

Tim Springer Lab - Congrats to Tim Springer who will receive the 2022 Founders Award from the Biophysical Society! bit.ly/3mvzoXZ

Wesley Wong and Tim Springer’s labs use single-molecule imaging to explain how von Willeband factor is able to self-associate to enable its key function in blood clotting. Wesley Wong Lab Tim Springer Lab bit.ly/31pXgFT

Interested in growth factor latency? Here a comparative survey of cross-armed, V-armed, and open-armed TGF-β family members from Tim Springer Lab Protection of the prodomain α1-helix correlates with latency in the tr... sciencedirect.com/science/articl…

At Biophysical Society's #bps2022 this week, @IPI_Protein co-founder timothy springer was awarded the 2022 Founder's Award for his innovations in #immunology, including his work on #integrins. Congratulations, Tim and Tim Springer Lab! 🎉 Story: biophysics.org/news-room/timo…

Congratulations Richard O. Hynes, Erkki Ruoslahti, and Timothy A. Springer, 2022 #LaskerAward winners! — “for discoveries concerning the #integrins—key mediators of cell-matrix and cell-cell adhesion in physiology and disease”. Massachusetts Institute of Technology (MIT) Sanford Burnham Prebys Harvard Medical School #Lasker2022

timothy springer Lasker Foundation With Richard Hynes & Erkki Ruoslahti, Springer discovered integrins, cell surface proteins that enable cells to interact with their surroundings Today, IPI is creating antibodies that can bind to integrins to accelerate #basicresearch and #drugdiscovery proteininnovation.org/2022/09/integr…

2 Boston-area scientists win prestigious Lasker Awards for cell research - discovery of integrins. Tim Springer Lab & Richard Hynes. bostonglobe.com/2022/09/28/nat… via The Boston Globe

Acceptance remarks from Lasker Foundation #LaskerAward winners Richard Hynes, Erkki Ruoslahti, and timothy springer for their discoveries concerning #integrins—key mediators of cell-matrix and cell-cell adhesion in physiology and disease: laskerfoundation.org/winners/integr…

Recent research by Myung Hyun Jo Taekjip Ha Xuefeng Wang @timspringerlab & Institute for Protein Innovation shows exactly how #integrins harness chemical cues and respond to physical forces. Curious how it works? Read more here 👇 proteininnovation.org/2023/03/integr…

Tim Springer is focused on his existing roster of commitments — running a research laboratory of more than a dozen people Tim Springer Lab, overseeing three NIH grants and sitting on six boards, including @SelectaBio, MorphicTx, Tectonic Therapeutic and Seismic Therapeutic endpts.com/with-moderna-w…

🎉 IPI has partnered with Addgene to provide biomedical researchers worldwide with access to well-validated #antibodies and other reagents, and expertise on how to use them. Look out for our release of a set of #integrin antibodies this fall! Read more: proteininnovation.org/2023/06/addgen…

Transforming growth factor (TGFß) is key regulator: immune system, development. There are 3 TGFß's; 1,2,3. Springer Boston Children's @HarvardMed use ATUM constructs. Show TGFß2 is activated by separate integrin. New opportunities for treating fibrosis pnas.org/doi/10.1073/pn…

A specialized integrin-binding motif enables proTGF-β2 activation by integrin αVβ6 but not αVβ8 pubmed.ncbi.nlm.nih.gov/37279271/

Proteins need to breathe: Stabilising conformations in a #malaria #parasite surface protein stops #Plasmodium #sporozoite migration and blocks transmission. Our latest collaboration with Tim Springer Lab out EMBO Reports. 'Fixing' TRAP 'kills' the parasite. doi.org/10.15252/embr.…

Don't forget! Join IPI Surfacing tomorrow at Harvard Medical School. Networking, discussion, posters & talks👇 🧪Christopher Garcia, Stanford University 🧪Yvonne Jones, University of Oxford 🧪Debora Marks, Harvard University 🧪Andreas Plückthun, University of Zurich 🧪Junichi Takagi, The University of Osaka proteininnovation.org/ipisurfacing/?…

Harvard Medical School Stanford University University of Oxford Debora Marks Harvard University University of Zurich The University of Osaka Hear a panel on synthetic #antibodies & #OpenScience 👇 🧪Errik Anderson, Alloy Therapeutics, Inc. 🧪aled edwards, Structural Genomics Consortium (SGC) & University of Toronto 🧪Andrew Kruse, Harvard Medical School 🧪Rob Meijers, IPI #Antibody Platform director 🧪Andreas Plückthun, University of Zurich 🧪Meghan Rego, Addgene proteininnovation.org/ipisurfacing/?…

Thanks Institute for Protein Innovation for sharing our work!

A new @nature #cryoEM study on #SARS-CoV-2 details the postfusion spike in a #lipidbilayer, defining the structure of critical membrane-interacting segments that may guide intervention strategies From researchers Institute for Protein Innovation Harvard Medical School & more ⬇️ nature.com/articles/s4158…