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In collaboration with UK Biobank & others, we’ve helped to complete the world’s largest exome sequencing of 470K+ participants. This will serve as a global resource as we work to improve scientific understanding of the genetic drivers of disease through accessible genomic data.

Latest discovery from Regeneron Genetics Center "Rare coding variants in CIDEB were associated with a decreased risk of liver disease across different underlying causes and different degrees of severity, including cirrhosis of any cause (odds ratio per allele, 0.50; 95% CI, 0.36 to 0.70)"

Today at #IGES22 our Senior Director of Statistical Genetics, @Timothy71925406, led the keynote address on the challenges and opportunities of diversity in large-scale sequencing studies. Our multi-ancestry sequencing has built the most diverse collection of human data to date.

Whole genome sequencing (WGS) vs. whole exome sequencing plus array genotyping and imputation (WES+IMP), which one is more cost-effective for population-scale genetic association studies? My colleagues at Regeneron Genetics Center (Gaynor et al.) answer this question using a

Today we, along with our collaborators at Unidad de Investigación en Medicina Experimental, Oxford Population Health (OxPop), AstraZeneca and @Abbvie are proud to share that our analysis of 140K individuals from the Mexico City Prospective Study (MCPS) has been published in nature. Explore the details: go.nature.com/3rStgzB

Today, we announced the launch of the Together for CHANGE™ initiative, a 10-year collaborative pledge working to address health disparities and promote health in Black communities. Our mission? To increase diversity in genetic research and STEM careers.

Whole genome sequencing (WGS) and whole exome sequencing (WES) have championed genomic discovery, but how do they compare? Published in nature, our team analyzed ~150K UK Biobank participants to study WGS vs. WES, and their impacts on discovery in genetic association studies.